Novel strategy for obtaining uniformly dispersed silver nanoparticles on soluble cotton wound dressing through carboxymethylation and in-situ reduction: antimicrobial activity and histological assessment in animal model

Wu, Tianyi; Lu, Fei; Wen, Qiuhan; Yu, Kun; Lu, Bitao; Bao, Rong; Dai, Fangyin; Lan, Guangqian

doi:10.1007/s10570-018-1907-z

Cited by 25 publications

(11 citation statements)

References 33 publications

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“…These scaffolds are utilized mainly for bone regeneration [ 160 ] and wound dressings. [ 161 ] For bone tissue engineering, chitosan/nanohydroxyapatite bio‐nanocomposite scaffolds containing Ag nanoparticles exhibited antimicrobial activities against Gram‐positive and Gram‐negative bacteria with negligible toxicity to rat osteoprogenitor cells and human osteosarcoma cells. [ 162 ] Antibacterial bioactive glass‐substituted Ag 2 O nanoparticles have been employed for bone regeneration as fillers in bone graft nanocomposites.…”

Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

483

368

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Microbial colonization on material surfaces is ubiquitous. Biofilms derived from surface-colonized microbes pose serious problems to the society from both an economical perspective and a health concern. Incorporation of antimicrobial nanocompounds within or on the surface of materials, or by coatings, to prevent microbial adhesion or kill the microorganisms after their attachment to biofilms, represents an important strategy in an increasingly challenging field. Over the last decade, many studies have been devoted to preparing meta-based nanomaterials that possess antibacterial, antiviral, and antifungal activities to combat pathogen-related diseases. Herein, an overview on the state-of-the-art antimicrobial nanosized metal-based compounds is provided, including metal and metal oxide nanoparticles as well as transition metal nanosheets. The antimicrobial mechanism of these nanostructures and their biomedical applications such as catheters, implants, medical delivery systems, tissue engineering, and dentistry are discussed. Their properties as well as potential caveats such as cytotoxicity, diminishing efficacy, and induction of antimicrobial resistance of materials incorporating these nanostructures are reviewed to provide a backdrop for future research.

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Section: Metal‐based Nanocompoundsmentioning

confidence: 99%

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Makvandi

Wang

Zare

et al. 2020

Adv Funct Materials

483

368

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show abstract

“…Similarly, chitosan blended with metallic nanoparticles has an eff ect on the microbial activity and wound healing [98]. Th e reductions of infl ammatory cells and mostly closed capillary lumens have been investigated by diverse research groups, using silver nanoparticles in diverse polymer matrices [89][90][91][92][93][94][95][96][97].…”

Section: Electrospinnable Polymer Materials For Wound Dressing Applicmentioning

confidence: 99%

“…Confocal laser scanning microscope (CLSM) images of (a) PAN/gelatine nanofi brous mat and (b) CHO-DP12 (Chinese hamster ovary) cells on PAN/gelatine nanofi brous mat, coloured with methylene blue on scale bar indicates 20 μmTekstilec, 2019, 62(2),[89][90][91][92][93][94][95][96][97][98][99][100] …”

mentioning

confidence: 99%

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

Mamun¹

2019

TEK

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Skin is an important part of the human body. Its function is to control the body's homeostasis mechanism. If a skin injury occurs, it is of utmost importance to heal the skin as soon as possible. The currently available medical treatment system, however, has limited eff ectiveness on the regeneration of the structure and function of the injured skin, potentially causing wound infections and dehydration. The corresponding impact on the healing process may in the worst case also be fatal. To overcome these problems in wound dressing materials, nanofi brous mats are excellent candidates for wound treatment and management. Such wound dressings can be found in biomedical applications not only in drug delivery, but also as antibacterial and antimicrobial materials, and as materials for the regeneration and repair of tissue or organs. The large surface-area-to-volume ratio is one of the unique properties of nanofi brous mats. This paper gives a brief overview of possible materials and applications of nanofi brous mats for wound dressing.

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“…However, the release of Ag NPs and Ag + ions during their use is a crucial issue because it may decrease the textile antibacterial effect over time, and may also represent a danger for the patient’s safety and the environment. Therefore, many studies have tried to understand how Ag NPs exert their antimicrobial activity and their possible toxic effects on humans, particularly because Ag NPs are the most frequent choice of antimicrobial material for medical textiles [ 20 ]. Ag NPs antibacterial activity towards Gram-negative (G−) and Gram-positive (G+) bacteria is mediated by the production of reactive oxygen species [ 8 ] that lead to damage of the bacterial cell proteins and DNA, and ultimately to the destruction of the bacterial membrane [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Multifunctional Hydroxyapatite/Silver Nanoparticles/Cotton Gauze for Antimicrobial and Biomedical Applications

et al. 2021

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Medical textiles have played an increasingly important protection role in the healthcare industry. This study was aimed at improving the conventional cotton gauze for achieving advanced biomedical specifications (coloration, UV-protection, anti-inflammation, and antimicrobial activities). These features were obtained by modifying the cotton gauze fabrics via in-situ precipitation of hydroxyapatite nanoparticles (HAp NP), followed by in-situ photosynthesis of silver (Ag) NPs with ginger oil as a green reductant with anti-inflammation properties. The HAp-Ag NPs coating provides good UV-protection properties. To further improve the HAp and Ag NPs dispersion and adhesion on the surface, the cotton gauze fabrics were modified by cationization with chitosan, or by partial carboxymethylation (anionic modification). The influence of the cationic and anionic modifications and HAp and Ag NPs deposition on the cotton gauze properties (coloration, UV-protection, antimicrobial activities, and water absorption) was thoroughly assessed. Overall, the results indicate that chemical (anionic and cationic) modification of the cotton gauze enhances HAp and Ag NPs deposition. Chitosan can increase biocompatibility and promotes wound healing properties of cotton gauze. Ag NP deposition onto cotton gauze fabrics brought high antimicrobial activities against Candida albicans, Gram-positive and Gram-negative bacteria, and improved UV protection.

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Novel strategy for obtaining uniformly dispersed silver nanoparticles on soluble cotton wound dressing through carboxymethylation and in-situ reduction: antimicrobial activity and histological assessment in animal model

Cited by 25 publications

References 33 publications

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Metal‐Based Nanomaterials in Biomedical Applications: Antimicrobial Activity and Cytotoxicity Aspects

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

Multifunctional Hydroxyapatite/Silver Nanoparticles/Cotton Gauze for Antimicrobial and Biomedical Applications

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