Novel smart chiral magnetic microspheres for enantioselective adsorption of tryptophan enantiomers

Chiral magnetic-nanobiofluids for rapid electrochemical screening of enantiomers at a magneto nanocomposite graphene-paste electrode

“…Nanosized gold particles posses water-solubility, high chemical stability and allows fine-tuning of the surface biocompatibility (Wang et al 2008), (Kharisov et al 2014). Thus, CF-NPs and their functionalized derivates have been exploited for their surface modification with a variety of functional (bio)molecules (i.e., cellulose derivates, proteins and β-CDs), presenting interesting potential in drug delivery, catalysis, magnetic response image, bioanalysis and emphasizing its chiral recognition capability towards the discrimination of amino acids enantiomers (Guo et al 2017), (Ghosh et al 2013), (Liu et al 2015). However, to the best of our knowledge, there has been only one recent work on their application for electrochemical chiral recognition (Shi et al 2017).…”

Decorated single-enantiomer phosphoramide-based silica/magnetic nanocomposites for direct enantioseparation

“…[25][26][27][28] Since their discovery, silica-based materials have emerged as a source of immense potential for applications like for example in selective adsorption, separation, catalysis, and preparation of novel functional materials. [29][30][31][32][33][34][35][36] Chemically modiable surfaces and superparamagnetic property of magnetic modied silica nanoparticles have attracted much attention. 31,[37][38][39][40][41] The usefulness of magnetic adsorbents is due to their easily and rapidly separation under an external magnetic eld, and in such purposes Fe 2 O 3 nanorods, Fe 3 O 4 and Fe-Pt alloy nanoparticles, and Fe 3 O 4 -polymer composites were studied.…”

“…Direct separation of enantiomers via such decorated magnetic nanomaterials would show great advantages compared with traditional methods of chiral separation. 29,57 One example is the application of R(+)-amethylbenzylamine-modied magnetic chiral sorbent in enantioseparation of mandelic acid. 58 From our previous studies on phosphorus-oxygen, phosphorus-nitrogen and phosphorus-sulfur compounds, [59][60][61][62][63][64] the P]O group was found as the best hydrogen-bond acceptor with respect to the other possible acceptor groups which usually exist in the molecules, typically C]O, S]O, N-O, P]S, ester and ether oxygen atoms, nitrogen, and p-system, examined with Xray diffraction study, statistical analysis based on the data deposited in the Cambridge Structural Database (CSD) 65,66 and quantum chemical calculations in some cases.…”

“…Direct separation of enantiomers via such decorated magnetic nanomaterials would show great advantages compared with traditional methods of chiral separation. 29,57 One example is the application of R (+)-α-methylbenzylamine-modified magnetic chiral sorbent in enantioseparation of mandelic acid. 58 …”

A novel surface plasmon resonance sensor based on a functionalized graphene oxide/molecular-imprinted polymer composite for chiral recognition of l-tryptophan

“…[4][5][6][7] However, the disadvantages of these approaches, which include expensive instrumentation, laborious sample pretreatments, and complicated derivatization procedures, impede their broad application. 2,8 As powerful analytical tools, surface plasmon resonance (SPR) sensors have enjoyed widespread attention over the past two decades because of their high sensitivity, low cost, and compact design. 9 SPR, a refractive index-based detection technique for real-time and label-free monitoring of ligand-receptor interactions on metal surfaces, [10][11][12][13] has been extended to the molecular imprinting eld.…”