2015
DOI: 10.1016/j.ejmech.2014.12.040
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Novel sesquiterpenes from Schisandra grandiflora: Isolation, cytotoxic activity and synthesis of their triazole derivatives using “click” reaction

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Cited by 26 publications
(13 citation statements)
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“…The in vitro anti-proliferative activity of isolates and its derivatives were examined against HeLa, PANC1, MDAMB-231, IMR32, HepG2 and SKNSH cell lines using the SRB assay [9]. Doxorubicin was used as the reference standard and the results are summarized in Table 3.…”
Section: Accepted M Manuscriptmentioning
confidence: 99%
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“…The in vitro anti-proliferative activity of isolates and its derivatives were examined against HeLa, PANC1, MDAMB-231, IMR32, HepG2 and SKNSH cell lines using the SRB assay [9]. Doxorubicin was used as the reference standard and the results are summarized in Table 3.…”
Section: Accepted M Manuscriptmentioning
confidence: 99%
“…As part of our continuous endeavors of phytochemical-pharmacological integrated studies on the Indian medicinal plants [7][8][9], we focused on the investigation of limonoid constituents from plants of the Meliaceae family, and recently reported the isolation and characterization of few new compounds from seeds of Cipadessa baccifera [10][11]. In the present work, to obtain the minor components, we decided to increase the amount of plant material and to reinvestigate the chemical constituents of the seed extract.…”
Section: Introductionmentioning
confidence: 99%
“…Plants of Schisandraceae are rich in triterpenoids, which showed various beneficial effects such as anti-HIV activity [2,3], cytotoxicity [4], antiplatelet aggregation [5], anti-HBV activity [6], and antagonistic effect [7]. Several sesquiterpenoids isolated from Schisandraceae family have also been found to possess significant cytotoxic activity [8][9][10] and anti-HBV activity [11].…”
Section: Introductionmentioning
confidence: 96%
“…In the last few decades, phytochemical work on the family Schisandraceae has resulted in a seminal contribution to novel structural frameworks for triterpenoidal skeletons [1,2,3,4]. Recently, some promising sesquiterpenes has also been reported from the plants of family Schisandraceae [5,6,7,8,9,10]. In our previous research, we reported the identification of several bioactive lignanoids from the genus kadsura [11] that highlight the immense diversity in the chemical constituents of these plants as well as in their important biological activities.…”
Section: Introductionmentioning
confidence: 99%