Novel pulp capping material based on sodium trimetaphosphate: synthesis, characterization, and antimicrobial properties

Franzin, Nayara Rodrigues Sartori; Sostena, Michela Melissa Duarte Seixas; Santos, Alailson Domingos dos; Aouada, Márcia Regina de Moura; Camargo, Emerson R.; Hosida, Thayse Yumi; Delbem, Alberto Carlos Botazzo; Moraes, João Carlos Silos

doi:10.1590/1678-7757-2021-0483

Cited by 6 publications

(2 citation statements)

References 40 publications

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“…CMET may be a very promising adjuvant for pulp-capping materials. Franzin et al [57] evaluated the mechanical, physicochemical and antimicrobial properties of a novel pulp capping material based on sodium trimetaphosphate. The experimental groups were two micro-(mTMP) and two nanoparticulate sodium trimetaphosphate (nTMP) groups, each containing zirconium oxide (ZrO 2 ), and a solution containing either chitosan or titanium oxide (TiO 2 ) nanoparticles (NPs).…”

Section: Discussionmentioning

confidence: 99%

Examination of surface porosity of current pulp capping materials by micro-computed tomography (micro-CT) method

2024

JOCPD

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When dental pulp is exposed, it must be covered with a biocompatible material to form reparative dentine. The material used, besides being biocompatible, should have an ideal surface structure for the attachment, proliferation and differentiation of dental pulp stem cells. This study aimed to evaluate the porosity of the microstructures of four pulp capping materials using micro-computed tomography (micro-CT). Biodentine, Bioaggregate, TheraCal and Dycal materials were prepared according to the manufacturer's instructions using 2 × 9 mm Teflon molds. A total of 60 samples, 15 in each group, were scanned using micro-CT. Open and closed pores and the total porosity of the microstructures of the materials were assessed. The findings obtained from the study were analyzed via the Kruskal-Wallis test followed by the Mann-Whitney U test. The porosity of Bioaggregate was significantly higher than that of Biodentine, Dycal and TheraCal in all porosity values. While Biodentine did not show a statistically significant difference in open and total porosity values from either TheraCal or Dycal, closed porosity values of Dycal were significantly higher than those of Biodentine and TheraCal. Because of the affinity of cells to porous surfaces, the pulp capping materials' microstructure may affect the pulp capping treatment's success. From this perspective, the use of Bioaggregate in direct pulp capping may increase the success of treatment.

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Section: Discussionmentioning

confidence: 99%

Examination of surface porosity of current pulp capping materials by micro-computed tomography (micro-CT) method

2024

JOCPD

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“…Comparison studies of different dental pulp capping formulations, including ZrO, TiO 2 , microTMP, and Nano-TMP, exhibited that formulations including Micro-TMP and Nano-TMP reduced setting times by about 50 %, and a reduction in TMP particle size increased their anti-cavity potential. Moreover, studies have shown that all investigated formulations showed antimicrobial activity against S. mutan s and L. casei [ 164 ]. Nanoscale compounds as an F alternative toothpaste formulation have gained popularity in the last decade due to their ability to reduce dental mineral loss.…”

Section: Nanomaterialsmentioning

confidence: 99%

Nanotechnology in toothpaste: Fundamentals, trends, and safety

Abedi,

Ghasemi,

Nemati

2024

Heliyon

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Unraveling Nanomaterials in Biomimetic Mineralization of Dental Hard Tissue: Focusing on Advantages, Mechanisms, and Prospects

Dai,

Li,

Zhang

2024

Advanced Science

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The demineralization of dental hard tissue imposes considerable health and economic burdens worldwide, but an optimal method that can repair both the chemical composition and complex structures has not been developed. The continuous development of nanotechnology has created new opportunities for the regeneration and repair of dental hard tissue. Increasingly studies have reported that nanomaterials (NMs) can induce and regulate the biomimetic mineralization of dental hard tissue, but few studies have examined how they are involved in the different stages, let alone the relevant mechanisms of action. Besides their nanoscale dimensions and excellent designability, NMs play a corresponding role in the function of the raw materials for mineralization, mineralized microenvironment, mineralization guidance, and the function of mineralized products. This review comprehensively summarizes the advantages of NMs and examines the specific mineralization mechanisms. Design strategies to promote regeneration and repair are summarized according to the application purpose of NMs in the oral cavity, and limitations and development directions in dental hard tissue remineralization are proposed. This review can provide a theoretical basis to understand the interaction between NMs and the remineralization of dental hard tissue, thereby optimizing design strategy, rational development, and clinical application of NMs in the field of remineralization.

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Novel pulp capping material based on sodium trimetaphosphate: synthesis, characterization, and antimicrobial properties

Cited by 6 publications

References 40 publications

Examination of surface porosity of current pulp capping materials by micro-computed tomography (micro-CT) method

Examination of surface porosity of current pulp capping materials by micro-computed tomography (micro-CT) method

Nanotechnology in toothpaste: Fundamentals, trends, and safety

Unraveling Nanomaterials in Biomimetic Mineralization of Dental Hard Tissue: Focusing on Advantages, Mechanisms, and Prospects

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