Novel porphyrin derivative containing cations as new photodynamic antimicrobial agent with high efficiency

Abstract

A new photosensitizer consisting of ammonium salt, TMP(+) was synthesized and achieved the synergistic effect of photodynamic and chemical antibacterial activity. Experiments showed promising bactericidal properties, while accelerating the healing of Staphylococcus aureus infected mice.

Anti-Inflammatory and Antithrombotic Potential of Metal-Based Complexes and Porphyrins

“…For example, the porphyrin ring in chlorophyll captures photons of light, initiating the process of converting light energy into chemical energy, which fuels plant growth and sustains life on Earth [23]. Moreover, porphyrins find diverse applications in scientific research, from medical and therapeutic fields to energy-related studies [24][25][26][27][28][29][30]. More specifically, synthetic porphyrins have become of particular interest in medicinal chemistry because they can form chelating compounds with certain toxic heavy metals or radioisotopes that emit gamma rays [22].…”