Novel oxazolones incorporated azo dye: Design, synthesis photophysical-DFT aspects and antimicrobial assessments with In-silico and In-vitro surveys

Synthesis and pharmacological activities of azo dye derivatives incorporating heterocyclic scaffolds: a review

“…According to Albelwi et al , novel azo dye-containing derivatives of the oxazolone compounds were obtained via the Erlenmeyer reaction of the azo dye precursors. 30 The new 4-arylidene-5-(4 H )-oxazolone azo chromophore 63 was produced by the condensation of 2-(4-(4-((2-hydroxyethyl)(methyl)amino)phenyl)diazenyl) acetic acid 61 with the corresponding benzaldehydes 62 in the presence of acetic anhydride and sodium acetate, as shown in Scheme 13. Compound 61 was formed from the diazotization of compound 58 followed by the coupling of compound 60. The formation of the unsaturated 5-[4 H ]-oxazolone was elucidated via a two-step mechanism.…”

A DFT analysis of electronic, reactivity, and NLO responses of a reactive orange dye: the role of Hartree-Fock exchange corrections

“…Azo compounds are π-systems made up of aromatic rings connected by azo-bridges (−N=N−) which behave like an entire pushpull system, favoring the electronic polarization. Because of their reactivity, these chromophores are often applied as antiviral and antifungal drugs [29][30][31]. The reactive orange (RO16) present in Fig.…”

Newly Synthesized Aminothiazole Based Disazo Dyes and Their Theoretical Calculations

“…It was observed that with the coupling of heterocyclic compounds to azo dyes, they exhibited biological activity and are used in many areas as antitumor, antifungal and antibacterial etc. agents [7][8][9][10][11][12][13]. Although there are many studies in the literature on biological agents, studies on the discovery of new agents are still ongoing.…”