Novel Oral Anticoagulants in Direct Current Cardioversion for Atrial Fibrillation

Comparison of Effectiveness and Safety of Antiarrhythmic Drugs Class IC and III in Patients After Electrical Cardioversion

“…The incidence of cardiovascular risk factors in the study population was consistent with world literature (Pisters et al, 2012;Femia et al, 2017).…”

“…Observed adverse reactions after six months were: six (3.6%) patients reported nausea, four (2.4%) had minor bleeding, six (3.6%) had cough and six (3.6%) had oedema. The frequency of bleeding caused by antithrombotic agents in our study was found to be lower than reflected in world literature (Camm et al, 2014;Femia et al, 2017). Only 2.4% of patients complained about minor bleeding and none of the patients experienced serious, life-threatening bleeding.…”

“…Patients had found out about their condition while undergoing routine check-ups. The frequency of recurrence of atrial fibrillation in patients after six months corresponds to world literature (Femia et al, 2017). After six months, 64 (38.0%) patients had been hospitalised, and for 48 (28.6%) patients the cause of hospitalisation was arrhythmia.…”

Cardioversion of atrial fibrillation and atrial flutter revisited: current evidence and practical guidance for a common procedure

“… 101–103 Similar to the results of the prospective studies and meta-analyses, several cohort studies with different post-procedural follow-up times and settings also demonstrated very low rates of thromboembolic events (0.15–1.62%) and major bleeding (0.4–1.7%) in patients with AF undergoing cardioversion during NOAC treatment suggesting that NOACs are associated with an acceptable benefit-risk profile in this setting. 94 , 95 , 104–108 Moreover, a pre-specified post hoc analysis of the ENSURE-AF study found that patients receiving edoxaban were more satisfied with their treatment than patients on warfarin. 109 Of note, the use of NOACs also lead to faster cardioversion compared to warfarin use when pursuing a standard care approach.…”

Efficacy and safety of direct oral anticoagulants in patients undergoing elective electrical cardioversion: A real-world patient population

“…In many centers, however, preprocedural imaging is not standard practice. Therefore, availability of real-world studies of pericardioversion DOAC is important [10][11][12][13][14][15][16][17][18]. Of these real-world studies, 2 single-center studies had a larger sample size than our study, however, in both studies approximately one-fifth of procedures were guided by TEE [11,17].…”