Novel Optical Position Sensing for Miniaturized Applications and Validation in a Total Artificial Heart

Pelletier, Benedikt A.; Blaszczyk, Yvonne M.; Carstens, Patrick; Álvarez, Gonzalo; Lamping, Felix; Laumen, Marco; Finocchiaro, Thomas; Steinseifer, Ulrich

doi:10.1109/tbme.2015.2463729

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Therefore, the MCL must contain both systemic and pulmonary circulation loops. The TAH assembled within an MCL system is normally tested for performance evaluation ( Castañeda et al, 1964 ; Kito et al, 1976 ; duPlessis and Tsang, 1977 ; Shiose et al, 2010 ; Pelletier et al, 2015 ; Pelletier et al, 2016 ; Tozzi et al, 2017 ), control strategy optimization ( Wang et al, 1987 ; Nabel et al, 1990 ), malfunction evaluation ( Makino et al, 2006 ), and durability test ( Zapanta et al, 2005 ) prior to animal experiment or clinical test. In the design of the MCL targeting TAH tests, a series of achievements were formed ( Donovan, 1975 ; Minamitani et al, 1978 ; High et al, 1979 ; Imachi et al, 1992a ; Imachi et al, 1992b ; Khalil et al, 2008 ; Fukamachi et al, 2010 ).…”

Section: Applications Of MCL For Cadmentioning

confidence: 99%

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

Gao

Wan³

et al. 2023

Front. Physiol.

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The mock circulatory loop (MCL) is an in vitro experimental system that can provide continuous pulsatile flows and simulate different physiological or pathological parameters of the human circulation system. It is of great significance for testing cardiovascular assist device (CAD), which is a type of clinical instrument used to treat cardiovascular disease and alleviate the dilemma of insufficient donor hearts. The MCL installed with different types of CADs can simulate specific conditions of clinical surgery for evaluating the effectiveness and reliability of those CADs under the repeated performance tests and reliability tests. Also, patient-specific cardiovascular models can be employed in the circulation of MCL for targeted pathological study associated with hemodynamics. Therefore, The MCL system has various combinations of different functional units according to its richful applications, which are comprehensively reviewed in the current work. Four types of CADs including prosthetic heart valve (PHV), ventricular assist device (VAD), total artificial heart (TAH) and intra-aortic balloon pump (IABP) applied in MCL experiments are documented and compared in detail. Moreover, MCLs with more complicated structures for achieving advanced functions are further introduced, such as MCL for the pediatric application, MCL with anatomical phantoms and MCL synchronizing multiple circulation systems. By reviewing the constructions and functions of available MCLs, the features of MCLs for different applications are summarized, and directions of developing the MCLs are suggested.

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Section: Applications Of MCL For Cadmentioning

confidence: 99%

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

Gao

Wan³

et al. 2023

Front. Physiol.

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Driver electronics design and control for a total artificial heart linear motor

Unthan

Cuenca-Navalon

Pelletier

et al. 2018

Med Biol Eng Comput

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For any implantable device size and efficiency are critical properties. Thus, a linear motor for a Total Artificial Heart was optimized with focus on driver electronics and control strategies. Hardware requirements were defined from power supply and motor setup. Four full bridges were chosen for the power electronics. Shunt resistors were set up for current measurement. Unipolar and bipolar switching for power electronics control were compared regarding current ripple and power losses. Here, unipolar switching showed smaller current ripple and required less power to create the necessary motor forces. Based on calculations for minimal power losses Lorentz force was distributed to the actor's four coils. The distribution was determined as ratio of effective magnetic flux through each coil, which was captured by a force test rig. Static and dynamic measurements under physiological conditions analyzed interaction of control and hardware and all efficiencies were over 89%. In conclusion, the designed electronics, optimized control strategy and applied current distribution create the required motor force and perform optimal under physiological conditions. The developed driver electronics and control offer optimized size and efficiency for any implantable or portable device with multiple independent motor coils. Graphical Abstract ᅟ.

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Novel Optical Position Sensing for Miniaturized Applications and Validation in a Total Artificial Heart

Abstract: Besides the use in a TAH, the presented PSS's can be employed in a wide use of miniaturized applications. The introduced testing method allows the validation for general miniaturized applications, e.g., linear motor drives.

Cited by 2 publications

References 12 publications

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

Mock circulatory loop applications for testing cardiovascular assist devices and in vitro studies

Driver electronics design and control for a total artificial heart linear motor

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