“…Methods for nitrite detection include spectrophotometry [1], chemiluminescence [2], chromatography [3], capillary zone electrophoresis [4] and electro-chemical methods [5][6][7][8]. Among these techniques, electro-chemical methods have proved to be effective approaches for measuring nitrite levels, due to the simplicity of instrumentation and operation.…”
We have investigated the oxidative electrochemistry of nitrite on glassy carbon electrodes modified with cobalt nanoparticles, poly(3,4-ethylenedioxythiophene) (PEDOT), and graphene. The modified electrode was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, and scanning electron microscopy. The results suggest that this new type of electrode combines the advantages of PEDOT-graphene films and cobalt nanoparticles and exhibits excellent electrocatalytic activity towards the oxidation of nitrite. There is a linear relationship between the peak current and the nitrite concentration in the range from 0.5 μM to 240 μM, and the detection limit is 0.15 μM. The modified electrodes also enable the determination of nitrite at low potentials where the noise level and interferences by other electro-oxidizable compounds are weak.
“…Methods for nitrite detection include spectrophotometry [1], chemiluminescence [2], chromatography [3], capillary zone electrophoresis [4] and electro-chemical methods [5][6][7][8]. Among these techniques, electro-chemical methods have proved to be effective approaches for measuring nitrite levels, due to the simplicity of instrumentation and operation.…”
We have investigated the oxidative electrochemistry of nitrite on glassy carbon electrodes modified with cobalt nanoparticles, poly(3,4-ethylenedioxythiophene) (PEDOT), and graphene. The modified electrode was characterized by cyclic voltammetry, electrochemical impedance spectroscopy, and scanning electron microscopy. The results suggest that this new type of electrode combines the advantages of PEDOT-graphene films and cobalt nanoparticles and exhibits excellent electrocatalytic activity towards the oxidation of nitrite. There is a linear relationship between the peak current and the nitrite concentration in the range from 0.5 μM to 240 μM, and the detection limit is 0.15 μM. The modified electrodes also enable the determination of nitrite at low potentials where the noise level and interferences by other electro-oxidizable compounds are weak.
“…On the other hand, electrochemical techniques can provide simple and cost-effective alternatives for selective and sensitive nitrite determination [15,16], providing a relatively safer and environmentally friendly approach with fewer reagents involved. These are mainly based on potentiometric [17], voltammetric [16] and amperometric [18] measurements. Although the nitrite ion is electroactive at carbon electrodes, its oxidation requires a high overvoltage where oxidisable compounds may interfere [19], hence catalytic modification of the electrode surface is required to lower this value.…”
The inside cover picture shows the catalytic degradation of a stem‐loop motif of the structured hepatitis C IRES RNA in an HCV‐infected liver cell. Catalytic metallodrugs promote irreversible degradation of the RNA and demonstrate significant antiviral activity in a cellular HCV replicon assay. MALDI‐TOF mass spectrometry combined with computational analysis provides insights into the site‐specific cleavage mechanism. For more details, see the Full Paper by James A. Cowan et al. on
“…Addition of 2% hexamethytrimethylammonium chloride (HTAC) as a suitable additive [16][17][18][19] increased the slope of the potential sensor response from a sub-Nernstian value of -51.1mV/decade (No. 4) to a Nernstian value of -59.8mV/decade (No.…”
Section: Table 1 Optimization Of Membrane Ingredientsmentioning
Abstract:A novel potentiometric membrane sensor has been developed and optimized based on 3,5,13,15-tetramethyl-4,14-diethyl-2,6,12,16,21,22-hexaazatricyclo [15.3. I 1-17 I 7-11 ] dicosa-1, (21),2,5,7,19,11(22),12,15,17,19-
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