Novel Nanoparticle-Based Treatment and Imaging Modalities

Taratula, Oleh; Taratula, Olena

doi:10.3390/pharmaceutics15010244

Cited by 3 publications

(4 citation statements)

References 23 publications

(22 reference statements)

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“…Additionally, the nanocarriers allowed for sustained release of the drugs, ensuring a prolonged and controlled treatment. 161 The nanocarrier is composed of compounds such as lipids or polymers, which are biocompatible and can easily penetrate the ectopic pregnancy tissue. The researchers also noted that the nanocarriers enhanced the stability of the drugs, preventing their degradation and increasing their bioavailability at the target site.…”

Section: Innovative Nanomedicine In Ectopic Pregnancymentioning

confidence: 99%

“…They found that this approach significantly improved the therapeutic efficacy of these drugs while minimizing their systemic side effects. Additionally, the nanocarriers allowed for sustained release of the drugs, ensuring a prolonged and controlled treatment . The nanocarrier is composed of compounds such as lipids or polymers, which are biocompatible and can easily penetrate the ectopic pregnancy tissue.…”

Section: Applications Of Nanotechnology-mediated Drug Delivery System...mentioning

confidence: 99%

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Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Acharya,

Behera,

Behera

et al. 2024

ACS Appl. Bio Mater.

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Over the past decade, nanotechnology has seen extensive integration into biomedical applications, playing a crucial role in biodetection, drug delivery, and diagnostic imaging. This is especially important in reproductive health care, which has become an emerging and significant area of research. Global concerns have intensified around disorders such as infertility, endometriosis, ectopic pregnancy, erectile dysfunction, benign prostate hyperplasia, sexually transmitted infections, and reproductive cancers. Nanotechnology presents promising solutions to address these concerns by introducing innovative tools and techniques, facilitating early detection, targeted drug delivery, and improved imaging capabilities. Through the utilization of nanoscale materials and devices, researchers can craft treatments that are not only more precise but also more effective, significantly enhancing outcomes in reproductive healthcare. Looking forward, the future of nanotechnology in reproductive medicine holds immense potential for reshaping diagnostics, personalized therapies, and fertility preservation. The utilization of nanotechnology-driven drug delivery systems is anticipated to elevate treatment effectiveness, minimize side effects, and offer patients therapies that are not only more precise but also more efficient. This review aims to delve into the various types, properties, and preparation techniques of nanocarriers specifically designed for drug delivery in the context of reproductive disorders, shedding light on the current landscape and potential future directions in this dynamic field.

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Section: Innovative Nanomedicine In Ectopic Pregnancymentioning

confidence: 99%

Section: Applications Of Nanotechnology-mediated Drug Delivery System...mentioning

confidence: 99%

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Acharya,

Behera,

Behera

et al. 2024

ACS Appl. Bio Mater.

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show abstract

“…Additionally, when given intravenously, MTX coupled with dendrimer nanoparticles has demonstrated encouraging outcomes for targeted delivery to inflammatory joints [62]. In addition to the studies using gold and dendrimer nanoparticles as carriers for the treatment of rheumatoid arthritis mentioned above, the simultaneous delivery of hydrophilic and hydrophobic drugs for the treatment of rheumatoid arthritis has also been investigated using chitosan/cyclodextrin nanoparticles [63]. Since gold nanoparticles are more effective and secure than traditional gold drugs, researchers are looking at using them as a delivery technique for RA therapy, particularly in the field of chrysotheraphy [64].…”

Section: Nano-particles As Carriers For Ros Regulation Therapiesmentioning

confidence: 99%

“…Since gold nanoparticles are more effective and secure than traditional gold drugs, researchers are looking at using them as a delivery technique for RA therapy, particularly in the field of chrysotheraphy [64]. According to these results, encapsulated nanoparticle carriers have considerable promise for enhancing the effectiveness and security of RA therapy [63].…”

Section: Nano-particles As Carriers For Ros Regulation Therapiesmentioning

confidence: 99%

Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling Pathways and Nano-Particles as Carriers

Srinivasan,

Ashok,

Sairam

et al. 2024

Reactive Oxygen Species - Advances and Developments

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Rheumatoid arthritis (RA) is a chronic and debilitating inflammatory condition characterized by joint degradation and permanent disability. Excessive production of reactive oxygen species (ROS) is implicated in RA pathogenesis, leading to oxidative stress and tissue damage. In recent years, nano-particles have emerged as promising carriers for ROS regulation therapies in RA treatment. This review explores the interplay between ROS and RA, emphasizing the importance of cell signaling pathways in ROS control. The potential of nano-particles as targeted drug delivery systems to scavenge excess ROS and restore redox equilibrium within affected cells is discussed. Preclinical studies using ROS-neutralizing nano-particles in RA animal models have shown significant reductions in joint inflammation and cartilage degradation. Clinical trials have further validated the safety and efficacy of nano-particle treatments in RA patients, leading to improved disease activity and joint function. The review highlights the benefits of nano-particle-based ROS control therapies, including improved drug solubility, prolonged drug delivery, reduced systemic side effects, and enhanced specificity for inflamed joints. However, further research is needed to fully understand the intricate mechanisms of ROS management in RA and optimize nano-particle production and delivery. Overall, nano-particle-based ROS control therapy holds great promise for revolutionizing RA treatment and improving the quality of life for affected individuals.

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History of Nanoparticles

Jetha,

Vyas,

Teli

et al. 2024

Nanocarrier Vaccines

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Novel Nanoparticle-Based Treatment and Imaging Modalities

Abstract: Over the last twenty years, nanomaterials have been widely used in cancer research [...]

Cited by 3 publications

References 23 publications

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Regulating Reactive Oxygen Species in Rheumatoid Arthritis: Insights into Cell Signaling Pathways and Nano-Particles as Carriers

History of Nanoparticles

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