Novel missense variants in brain morphogenic genes associated with depression and schizophrenia
Maxim Karagyaur,
Alexandra Primak,
Kirill Bozov
et al.
Abstract:IntroductionImpaired function of brain morphogenic genes is considered one of the predisposing factors for the manifestation of psychiatric and cognitive disorders, such as paranoid schizophrenia (SCZ) and major depressive disorder (MDD). Identification of such genes (genes of neurotrophic factors and guidance molecules among them) and their deleterious genetic variants serves as a key to diagnosis, prevention, and possibly treatment of such disorders. In this study, we have examined the prevalence of genomic … Show more
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