Novel Meals from Eastern Canada’s Marine Fishery By-products as Alternatives to Fishmeal

Plante, Sébastien; Béland, France; Tchoukanova, Nadejda; Gagnon, Jacques

doi:10.1080/10498850.2016.1201712

Cited by 4 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The PUFA fraction had an omega-3-to-omega-6 ratio of 10.7 and the omega-3 PUFA were predominantly EPA (8.0%) and DHA (10.8%). The amino acid composition of HPH had a very high level of arginine (11.4%) that alone amounted to 29% of the total amino acid fraction, which is consistent with a previously published report [17].…”

Section: Resultssupporting

confidence: 92%

Herring Milt Protein Hydrolysate Improves Insulin Resistance in High-Fat-Diet-Induced Obese Male C57BL/6J Mice

et al. 2019

Self Cite

View full text Add to dashboard Cite

Protein consumption influences glucose homeostasis, but the effect depends on the type and origin of proteins ingested. The present study was designed to determine the effect of herring milt protein hydrolysate (HPH) on insulin function and glucose metabolism in a mouse model of diet-induced obesity. Male C57BL/6J mice were pretreated with a low-fat diet or a high-fat diet for 6 weeks. Mice on the high-fat diet were divided into four groups where one group continued on the high-fat diet and the other three groups were fed a modified high-fat diet where 15%, 35%, and 70%, respectively, of casein was replaced with an equal percentage of protein derived from HPH. After 10 weeks, mice that continued on the high-fat diet showed significant increases in body weight, blood glucose, insulin, and leptin levels and exhibited impaired oral glucose tolerance, insulin resistance, and pancreatic β-cell dysfunction. Compared to mice fed the high-fat diet, the 70% replacement of dietary casein with HPH protein reduced body weight, semi-fasting blood glucose, fasting blood glucose, insulin, leptin, and cholesterol levels and improved glucose tolerance, homeostasis model assessment of insulin resistance (HOMA-IR), and homeostasis model assessment of β-cell function (HOMA-β) indices. The 35% replacement of dietary casein with HPH protein showed moderate effects, while the 15% replacement of dietary casein with HPH protein had no effects. This is the first study demonstrating that replacing dietary casein with the same amount of protein derived from HPH can prevent high-fat-diet-induced obesity and insulin resistance.

show abstract

Section: Resultssupporting

confidence: 92%

Herring Milt Protein Hydrolysate Improves Insulin Resistance in High-Fat-Diet-Induced Obese Male C57BL/6J Mice

et al. 2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…The analysis and chemical composition of HMPH were reported previously [ 21 , 24 ], and the same methods were used to analyze the composition of HMDP. It was revealed that HMDP contained 69% of crude protein, 11.2% of lipids, 13.8% of ash, and 6.0% of moisture, similar to HMPH that had 70.8% crude protein, 10.8% lipids, 12.7% ash, and 6.6% moisture.…”

Section: Resultsmentioning

confidence: 99%

Herring Milt and Herring Milt Protein Hydrolysate Are Equally Effective in Improving Insulin Sensitivity and Pancreatic Beta-Cell Function in Diet-Induced Obese- and Insulin-Resistant Mice

2020

Self Cite

View full text Add to dashboard Cite

Although genetic predisposition influences the onset and progression of insulin resistance and diabetes, dietary nutrients are critical. In general, protein is beneficial relative to carbohydrate and fat but dependent on protein source. Our recent study demonstrated that 70% replacement of dietary casein protein with the equivalent quantity of protein derived from herring milt protein hydrolysate (HMPH; herring milt with proteins being enzymatically hydrolyzed) significantly improved insulin resistance and glucose homeostasis in high-fat diet-induced obese mice. As production of protein hydrolysate increases the cost of the product, it is important to determine whether a simply dried and ground herring milt product possesses similar benefits. Therefore, the current study was conducted to investigate the effect of herring milt dry powder (HMDP) on glucose control and the associated metabolic phenotypes and further to compare its efficacy with HMPH. Male C57BL/6J mice on a high-fat diet for 7 weeks were randomized based on body weight and blood glucose into three groups. One group continued on the high-fat diet and was used as the insulin-resistant/diabetic control and the other two groups were given the high-fat diet modified to have 70% of casein protein being replaced with the same amount of protein from HMDP or HMPH. A group of mice on a low-fat diet all the time was used as the normal control. The results demonstrated that mice on the high-fat diet increased weight gain and showed higher blood concentrations of glucose, insulin, and leptin, as well as impaired glucose tolerance and pancreatic β-cell function relative to those on the normal control diet. In comparison with the high-fat diet, the replacement of 70% dietary casein protein with the same amount of HMDP or HMPH protein decreased weight gain and significantly improved the aforementioned biomarkers, insulin sensitivity or resistance, and β-cell function. The HMDP and HMPH showed similar effects on every parameter except blood lipids where HMDP decreased total cholesterol and non-HDL-cholesterol levels while the effect of HMPH was not significant. The results demonstrate that substituting 70% of dietary casein protein with the equivalent amount of HMDP or HMPH protein protects against obesity and diabetes, and HMDP is also beneficial to cholesterol homeostasis.

show abstract

“…This results in a total of six potential product classes: (1) Feed grade whole biomass, either live, (freeze)dried or frozen to be used as aquaculture feed, (2) Proteins for feed, (3) Fatty acids and lipids for feed, (4) Biomass as organic fertilizer, (5) Technical proteins for e.g. paint and adhesives, (6) Oleo-chemicals for e.g. soaps and detergents.…”

Section: From Food Waste To Worm Based Fish Feedmentioning

confidence: 99%

“…However, the longer chain fatty acids (≥ C20) present in fi shmeal are not provided by algae or BSF but only by Lv. (Ötleş and Pire, 2001;Plante et al, 2017;St-Hilaire et al, 2007) and chapter Production efficiencies can be compared in terms of feed conversion ratio's (FCR) and yield (Table 6.6). Because the production efficiency depends on several factors such as the quality of the substrate, growth conditions and physiology, a direct comparison is difficult.…”

Section: Worm Biomass Compared To Other Fishmeal Replacersmentioning

confidence: 99%

Valorisation of waste streams from by-product to worm biomass

Laarhoven¹

View full text Add to dashboard Cite

show abstract

Novel Meals from Eastern Canada’s Marine Fishery By-products as Alternatives to Fishmeal

Cited by 4 publications

References 24 publications

Herring Milt Protein Hydrolysate Improves Insulin Resistance in High-Fat-Diet-Induced Obese Male C57BL/6J Mice

Herring Milt Protein Hydrolysate Improves Insulin Resistance in High-Fat-Diet-Induced Obese Male C57BL/6J Mice

Herring Milt and Herring Milt Protein Hydrolysate Are Equally Effective in Improving Insulin Sensitivity and Pancreatic Beta-Cell Function in Diet-Induced Obese- and Insulin-Resistant Mice

Valorisation of waste streams from by-product to worm biomass

Contact Info

Product

Resources

About