Novel inhibition mechanism of carbapenems on the ACC-1 class C β-lactamase

Bae, Da Woon; Jung, Ye Eun; Jeong, Bo Gyeong; Shin, Sun

doi:10.1016/j.abb.2020.108570

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Secondary and Tertiary Structures1

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2021

2024

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“…The first crystallographic structure of an AmpC was reported in 1994, for the covalent complex between a phosphonate transition-state analog and the E. hormaechei P99 (formerly known as E. cloacae P99) cephalosporinase, which belongs to the ACT family (141). Many structures from different families of class C β-lactamases have since been published, including ACC (142,143), ACT (141,(144)(145)(146)(147)(148)(149)(150)(151)(152)(153)(154)(155)(156), ADC (103,(157)(158)(159)(160)(161)(162), CMH (163), CMY (154,(164)(165)(166)(167)(168), EC (165,, FOX (207)(208)(209), MOX (210,211), PDC Figure 2 here…”

Section: Secondary and Tertiary Structuresmentioning

confidence: 99%