Novel “GaEl Antigenic Patches” Identified by a “Reverse Epitomics” Approach to Design Multipatch Vaccines against NIPAH Infection, a Silent Threat to Global Human Health
Sukrit Srivastava,
Michael Kolbe
Abstract:Nipah virus (NiV) is a zoonotic virus that causes lethal
encephalitis
and respiratory disease with the symptom of endothelial cell–cell
fusion. Several NiV outbreaks have been reported since 1999 with nearly
annual occurrences in Bangladesh. The outbreaks had high mortality
rates ranging from 40 to 90%. No specific vaccine has yet been reported
against NiV. Recently, several vaccine candidates and different designs
of vaccines composed of epitopes against NiV were proposed. Most of
the vaccines target single p… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.