Novel fused pyran derivatives induce apoptosis and target cell cycle progression in anticancer efficacy against multiple cell lines
K. Fabitha,
Anoop Kallingal,
Natalia Maciejewska
et al.
Abstract:Nitrogen-based heterocycles such as pyrazole, imidazole, 1,2,4-triazole, benzimidazole, and benzotriazole substituted fused pyran derivatives (6a-e, 8a-e, 10a-e, 12a-e & 14a-e) have been synthesized and tested for their in vitro anticancer...
We introduce, for the first time, an inorganic base-mediated cyclization and auto-oxidation of bisallenones/bisalkynones. This reaction is realized under mild conditions through precise control of the base and atmosphere, providing...
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