Novel fibers fabricated directly from chitin solution and their application as wound dressing

Huang, Yao; Zhong, Zibiao; Duan, Bo; Zhang, Lina; Yang, Zixuan; Wang, Yanfeng; Ye, Qifa

doi:10.1039/c4tb00098f

Cited by 96 publications

(63 citation statements)

References 36 publications

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“…Notwithstanding the fact that the described self-assembly has proven to be viable, it would be better to use solvents exempt from toxicity and volatility. One approach is based on ionic liquids considered as green solvents capable to replace organic compounds [ 82 ], whilst the second approach is based on urea in alkaline solution [ 83 , 84 , 85 , 86 ]. In addition, self-assembled chitin nanofibers are important for the study of randomly oriented nanofiber networks.…”

Section: Advanced Approaches To the Preparation Of Chitin Nanofibrmentioning

confidence: 99%

Emerging Biomedical Applications of Nano-Chitins and Nano-Chitosans Obtained via Advanced Eco-Friendly Technologies from Marine Resources

2014

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The present review article is intended to direct attention to the technological advances made in the 2010–2014 quinquennium for the isolation and manufacture of nanofibrillar chitin and chitosan. Otherwise called nanocrystals or whiskers, n-chitin and n-chitosan are obtained either by mechanical chitin disassembly and fibrillation optionally assisted by sonication, or by e-spinning of solutions of polysaccharides often accompanied by poly(ethylene oxide) or poly(caprolactone). The biomedical areas where n-chitin may find applications include hemostasis and wound healing, regeneration of tissues such as joints and bones, cell culture, antimicrobial agents, and dermal protection. The biomedical applications of n-chitosan include epithelial tissue regeneration, bone and dental tissue regeneration, as well as protection against bacteria, fungi and viruses. It has been found that the nano size enhances the performances of chitins and chitosans in all cases considered, with no exceptions. Biotechnological approaches will boost the applications of the said safe, eco-friendly and benign nanomaterials not only in these fields, but also for biosensors and in targeted drug delivery areas.

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Section: Advanced Approaches To the Preparation Of Chitin Nanofibrmentioning

confidence: 99%

Emerging Biomedical Applications of Nano-Chitins and Nano-Chitosans Obtained via Advanced Eco-Friendly Technologies from Marine Resources

2014

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“…In contrast, Huang et al. synthesized chitin fibers and nonwoven fabric using NaOH/urea as the solvent . The chitin nonwoven fabric exhibited a more remarkable effect on wound healing than the traditional gauze.…”

Section: Ionic Liquid Technology For the Wet Spinning Of Polymer Blendsmentioning

confidence: 99%

Processing of Cellulose Using Ionic Liquids

Hermanutz

Vocht

Panzier

et al. 2018

Macro Materials & Eng

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The processing of cellulose dissolved in ionic liquids (ILs) enables the development of new materials. Besides the established production of cellulosic fiber products, interesting technical applications are developed like super micro filament fibers, cellulose/chitin blend fibers, precursors for carbon fibers, and all‐cellulose composites. This review provides a detailed summary of these new developments and describes how ILs are selected for the processing of cellulose with a particular emphasis on industrial realization. State‐of‐the‐art spinning processes are reviewed and it is illustrated how uniquely selected ILs can be used not only for established fiber spinning but for the development of new cellulose‐based materials.

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“…The porous nature of nanofibrous scaffolds enable excellent ability to absorb wound exudates, prevent the moisture loss around the wound, allow oxygen permeation, protect the wound from bacterial infection, and exhibit good conformability [562,563]. A diverse range of synthetic and natural polymers, including polyurethane (PU), PLA, PCL, PLGA, polyvinyl alcohol, dextran, chitin, chitosan, cellulose acetate, gelatin and collagen, have been exploited as candidates for dressing materials, where bioactive agents such as anti-inflammatory drugs and tissue growth agents were also incorporated in the polymeric nanofibers for controlled delivery [562,[564][565][566][567]].…”

Section: Wound Dressingmentioning

confidence: 99%

Polymeric nanostructured materials for biomedical applications

Tang

Tian

et al. 2016

Progress in Polymer Science

277

150

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Polymeric nanostructured materials (PNMs), which are polymeric materials in nanoscale or polymer composites containing nanomaterials, have become increasingly useful for biomedical applications. In specific, advances in polymer-related nanoscience and nanotechnology have brought a revolutionary change to produce new biomaterials with tailored properties and functionalities for targeted biomedical applications. These materials, including micelles, polymersomes, nanoparticles, nanocapsules, nanogels, nanofibers, dendrimers and nanocomposites, have been widely used in drug delivery, gene therapy, bioimage, tissue engineering and regenerative medicine. This review presents a comprehensive overview on the various types of PNMs, their fabrication methods and biomedical applications, as well as the challenges in research and development of future PNMs.

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Novel fibers fabricated directly from chitin solution and their application as wound dressing

Cited by 96 publications

References 36 publications

Emerging Biomedical Applications of Nano-Chitins and Nano-Chitosans Obtained via Advanced Eco-Friendly Technologies from Marine Resources

Emerging Biomedical Applications of Nano-Chitins and Nano-Chitosans Obtained via Advanced Eco-Friendly Technologies from Marine Resources

Processing of Cellulose Using Ionic Liquids

Polymeric nanostructured materials for biomedical applications

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