Novel extraction technique for L-DOPA from seeds of Mucuna pruriens

Stripping voltammetric methods for determination of the antiparasitic drug nitazoxanide in bulk form, pharmaceutical formulation and human serum

“…Based on the adsorption behavior of nitazoxanide onto the mercury electrode surface, simple and highly sensitive linear sweep, differential pulse and square wave adsorptive cathodic stripping voltammetric methods were developed for determination of nitazoxanide in bulk form, formulation "Cryptonaz powder" and in spiked human serum without the necessity for extraction [4][5][6][7][8][9][10] or formation of colored chromogens [11][12][13] prior to analysis. Nitazoxanide was also analyzed successfully without interferences from excipients or from its acid or base-induced degradation products.…”

“…Chromatographic [4][5][6][7][8][9][10] and spectrophotometric [11][12][13] analytical methods have been reported for determination of nitazoxanide in the bulk form as well as in pharmaceutical formulations. The reported chromatographic methods [4][5][6][7][8][9][10] necessitate sample pretreatment and time-consuming extraction steps prior to analysis of the drug. Moreover, these methods require expensive equipment and considerable skills are necessary to operate them successfully.…”

Development of a simple, rapid and validated spectrophotometric method for nitazoxanide in pharmaceutical formulations and comparison with HPLC

“…[7][8][9] Recently, methods for the estimation of NTZ in bulk and pharmaceuticals formulations were develope in visible spectrophotometry, 10 high-performance thin-layer chromatographiy (HPTLC) and LC. [11][12][13][14] Several of these methods require the use of hazardous and expensive chemicals, which make the process not only a challenge for the environment but also complex and time consuming. Chromatographic techniques are time consuming, costly and require expertise.…”