Novel Estrogen Receptor Inhibitory Mechanism for Halogen-containing Endocrine-disrupting Chemicals Discovered by Computer Simulation
Ayami Matsushima
Abstract:Bisphenol A (BPA) is a component used in the manufacture of polycarbonate plastics and epoxy resins around the world; however, it is also well─ known as one of the most notorious endocrine─ disrupting chemicals. To avoid using BPA as an ingredient, various BPA derivatives and related compounds have been synthesized and the use of these for making polymers has grown signi cantly; however, the safety of these BPA derivatives, also known as next─ generation bisphenols, has not been fully evaluated. We hypothesize… Show more
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