“…Future studies will be focused on determining which regions of these PDZ domain-containing proteins and other targets identified in this work, are important for the phospho-interaction with E7. Additionally, recent studies showed a regulation of DLG1 levels by HPV18 E7 and, moreover, phosphorylation of E7 by CKII modulates the redistribution and stabilization of DLG1 and hScrib [ 47 , 48 ]. These data, together with our results presented here, suggest a possible interplay of E6 and E7 with certain cellular targets.…”