Novel drug design and repurposing: An opportunity to improve translational research in cardiovascular diseases?
José S. Rodríguez‐Zavala,
Cecilia Zazueta
Abstract:Drug repurposing is defined as the use of approved therapeutic drugs for indications different from those for which they were originally designed. Repositioning diminishes both the time and cost for drug development by omitting the discovery stage, the analysis of absorption, distribution, metabolism, and excretion routes, as well as the studies of the biochemical and physiological effects of a new compound. Besides, drug repurposing takes advantage of the increased bioinformatics knowledge and availability of… Show more
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