Novel dinuclear NHC–gold(i)-amido complexes and their application in energy transfer photocatalysis

Abstract

The development of efficient and operationally simple synthetic routes to dinuclear gold(I)-amido complexes bearing aromatic/aliphatic-bridges are reported. This family of complexes was prepared utilizing environmentally friendly and sustainable reagents under...

Dinuclear NHC–gold(i)–thiolato and –alkynyl complexes: synthesis, anticancer activity, and catalytic activity in lactonization reactions

“…Based on our previous reports, 37,38 we initiated our investigation with the model substrate of [(IPr) o -xylene (AuBr) 2 ] 1a with 2.2 equiv. of thiophenol and 6 equiv.…”

“…This observation was also made in the previously observed reactivity/isolation of dinuclear NHC–gold( i ) carbazolyl complexes. 38…”

Synthesis of cyclohepta[b]indoles via gold mediated energy transfer photocatalysis

“…24 With high triplet energy values, namely 67.9 kcal mol −1 for PhotAuCat I and 67.6 kcal mol −1 for PhotAuCat II , these have demonstrated efficiency in diverse [2+2]-photocycloadditions, surpassing state-of-the-art Ir photocatalysts. 25–27…”

“…Recently, while exploring the intermolecular [2+2]-cycloaddition of indoles via gold-mediated EnT photocatalysis, we discovered the unexpected formation of cyclohepta[ b ]indole. 27 Considering the great interest in this scaffold, we now further explore this initial observation and report on an efficient protocol for its synthesis via gold-mediated energy transfer photocatalysis from functionalized indoles.…”

“…2) in a 64% yield in EtOAc after 18 hours (see ESI† for complete optimization studies, Table S1). 27 PhotAuCat I , being an efficient and easily accessible gold sensitizer, was tested under identical conditions, providing a 74% yield of 2a . An even higher yield (84%) was obtained by using i PrOAc as the solvent.…”