Novel Designing of Chemically Modified Electrode (CME) of the Bio‐MOF‐1 for the Detection of Dopamine Based on Inhibition of [Ru(bpy)₃]²⁺/DBAE System

Abstract

Metal organic frameworks (MOFs) have attracted extensive attention in electrochemical research fields due to their high surface area and controlled porosity. Current study is design to investigate the ECL performance of the chemically modified electrode (CME) based on the bio‐MOF‐1, a porous zinc‐adenine framework, which loaded ruthenium complex and employed for the detection of dopamine (DA). The composite material [Ru(bpy)3]2+@bio‐MOF‐1 (Ru‐bMOF) modified carbon glassy electrode (Ru‐bMOF/GCE) exhibited an excellent ECL performance having a linear co‐efficient response (R2=0.9968) for 2‐(dibutyl amino) ethanol (DBAE), a classical ECL co‐reactant was obtained over a concentration range of 1.0×10−9 M to 1.0×10−4 M in 0.10 M pH=6.0 phosphate buffer solution (PBS). Furthermore, DA was detected based on its inhibition effect on [Ru(bpy)3]2+/DBAE system. Compared to traditional analytical methods, this method has various advantages such as simple electrode preparation, quick response, high reproducibility (RSD<2.0 %), low limit of detection (LOD=1.0×10−10 mol/L). This chemical investigated modified electrode had exploited potential for detection of DA.