Novel coronavirus pneumonia and acute pulmonary thromboembolism: casualty or causality?

Beraldo, Gabriel Laverdi; Fonseca, Eduardo Kaiser Ururahy Nunes; Yokoo, Patrícia; Matos, Marina Justi Rosa de; Rosa, Marcela Emer Egypto; Silva, Murilo Marques Almeida; Chate, Rodrigo Caruso; Shoji, Hamilton; Ishikawa, Walther Yoshiharu

doi:10.31744/einstein_journal/2020ai5750

Cited by 4 publications

(4 citation statements)

References 6 publications

(11 reference statements)

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“…Patients may present with hypercoagulability, placing them at increased risk of thromboembolic events such as pulmonary thromboembolism and stroke 15 , 32 , 34 , 35 . A significant increase in D-dimer, an important marker of deep venous thrombosis, is also possible, and may be related to the development of intravascular hypercoagulability (71%) 36 , 37 . The associations between immobility, systemic inflammation, platelet activation, endothelial dysfunction, and blood stasis can lead to abnormalities in coagulation 38 .…”

Section: Factors That Influence Functional Capacity After Covid-19mentioning

confidence: 99%

“…Covid-19 patients presenting with the most severe form of the disease have also been known to develop disseminated intravascular coagulation (DIC) and are at an increased risk of death 36 . DIC occurs as consequence of an acute inflammatory response or sepsis, which leads to endothelial and tissue damage and, ultimately, to multiple organ failure 36 , 37 . Thus, the identification of patients with coagulopathy is of paramount importance to determine if anticoagulant therapy should be started to improve prognosis 33 .…”

Section: Factors That Influence Functional Capacity After Covid-19mentioning

confidence: 99%

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Functional capacity and rehabilitation strategies in Covid-19 patients: current knowledge and challenges

Frota

Vieira

Soares

et al. 2021

Rev. Soc. Bras. Med. Trop.

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Covid-19 is a novel infectious disease whose spectrum of presentation ranges from absence of symptoms to widespread interstitial pneumonia associated with severe acute respiratory syndrome (SARS), leading to significant mortality. Given the systemic pattern of Covid-19, there are many factors that can influence patient's functional capacity after acute infection and the identification of such factors can contribute to the development of specific rehabilitation strategies. Pulmonary impairment is the primary cause of hospitalization due to Covid-19, and can progress to SARS as well as increase length of hospitalization. Moreover, cardiac involvement is observed in approximately 30% of hospitalized patients, with an increased risk of acute myocarditis, myocardial injury, and heart failure, which may compromise functional capacity in the long-term. Thromboembolic complications have also been reported in some patients with Covid-19 and are associated with a poor prognosis. Musculoskeletal complications may result from long periods of hospitalization and immobility, and can include fatigue, muscle weakness and polyneuropathy. Studies that address the functional capacity of patients after Covid-19 infection are still scarce. However, based on knowledge from the multiple systemic complications associated with Covid-19, it is reasonable to suggest that most patients, especially those who underwent prolonged hospitalization, will need a multiprofessional rehabilitation program. Further studies are needed to evaluate the functional impact and the rehabilitation strategies for patients affected by Covid-19.

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Section: Factors That Influence Functional Capacity After Covid-19mentioning

confidence: 99%

Section: Factors That Influence Functional Capacity After Covid-19mentioning

confidence: 99%

Functional capacity and rehabilitation strategies in Covid-19 patients: current knowledge and challenges

Frota

Vieira

Soares

et al. 2021

Rev. Soc. Bras. Med. Trop.

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“…Table (5) Correlation between personal data of the studied postgraduate students and total post-covid-19 functional status scale showed that there was a highly significant correlation between the studied postgraduate students (age, gender, and hospital workplace) and total post-covid functional status scale with the presence of a significant correlation between (years of experience and educational level and length of hospital stay) and total post covid functional status scale.…”

Section: Table (4) Comparison Of Descriptive Statistics Of Post-covidmentioning

confidence: 93%

Prevalence of Functional Health Limitation among Post Graduate Students with Post -Covid-19 Syndrome: Instructional Module

Mahmoud,

Ali,

Mahmoud

2023

Egyptian Journal of Nursing and Health Sciences

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Background: Since the starting of coronavirus disease 2019 pandemic broke out, post-covid-19 survivors have received the majority of attention. globally, due to the association of high mortality rate and the presence of post-covid-19 syndromes with varying degrees of prolonged impairment of pulmonary function, muscle weakness, discomfort, exhaustion, depression, work-related issues, and a decreased quality of life. Aim: The study aims to assess the prevalence of functional health limitations among postgraduate students with post-covid-19 syndromes. Design: Longitudinal cohort; quasiexperimental retrospectively data collected from postgraduate students with post-covid-19 syndromes. Setting: Faculty of Nursing, Helwan University/Egypt Subjects: A purposive sample of 65 postgraduate students who were previously infected. Tools: (1) Post-covid-19 syndrome follow-up screening questionnaire, (2) Post-covid-19 functional status scale, and (3) Post-covid-19 rehabilitation screening. Results: 52.3% of studied students severely suffered from post-covid-19 diagnosis and mildly require constant care with (44.6% & 80.0%) of them forced to avoid needed duties/activities and experiencing functional health limitations post-covid-19 trauma. Conclusion: There was an improvement in the most of studied student covid-19 rehabilitation screening scale with a highly significant correlation between ages, gender, hospital workplace, and total postcovid-19 functional status scale with a significant correlation between experience years' experience, educational level, and length of hospital stay after instructional module carrying out. Recommendations: Establish a team approach to monitoring patients' postcovid-19, raising clinical awareness and home self-monitoring for preventing functional health limitations, and enhancing results.

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“…Studies indicate that infection alone, without the presence of associated risk factors, considerably increases the risk of PE, since patients infected with SARS-CoV-2 in severe stages have the three factors attributed to thrombosis, known as Virchow's triad (endothelial injury, reduced flow, hypercoagulation state) [4,6] . In laboratory tests, the propensity to clots is perceived by the increase in the levels of Ddimer, fibrinogen and other products of fibrin degradation -the first being an important marker not only for screening the diagnosis, but also for the patient's prognosis [6,7] . The present report aims to present a case of acute PE due to SARS-CoV-2 infection and to contribute with scientific knowledge since there are still many gaps to be understood about the manifestations of the disease and its evolution.…”

Section: Introductionmentioning

confidence: 99%

Radiological analysis of acute pulmonary thromboembolism as a consequence of COVID-19: A case report

Sampaio¹,

Gumieri²,

Bezerra³

et al. 2021

Int. J. Radiol. Diagn. Imaging

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SARS-CoV-2 is a virus of the coronavidae family that causes COVID-19, a disease that emerged in 2019 and has already gone around the world, causing the World Health Organization to decree a pandemic state in 2020. One of the consequences of COVID-19 is the development of Pulmonary Thromboembolism (PE), a disease in which one or more pulmonary arteries are blocked by a blood clot. In this association with COVID-19, PE is caused by the pro-inflammatory and hypercoagulant state developed by the SARS-CoV-2 infection. To analyze aspects of both diseases, imaging tests such as computed tomography (CT) and chest radiography (X-ray) are commonly used. CT and X-ray are considered first-line imaging tools to assess the decline in cases of COVID-19, and besides that, multidetector CT pulmonary angiography (CTPA) can assist in the confirmation or exclusion of PE. Therefore, this case report is about imaging findings that correlate COVID-19 and PE.

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Novel coronavirus pneumonia and acute pulmonary thromboembolism: casualty or causality?

Cited by 4 publications

References 6 publications

Functional capacity and rehabilitation strategies in Covid-19 patients: current knowledge and challenges

Functional capacity and rehabilitation strategies in Covid-19 patients: current knowledge and challenges

Prevalence of Functional Health Limitation among Post Graduate Students with Post -Covid-19 Syndrome: Instructional Module

Radiological analysis of acute pulmonary thromboembolism as a consequence of COVID-19: A case report

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