Novel Coronavirus Disease 2019 in a Patient on Durable Left Ventricular Assist Device Support

Singh, Rajat; Domenico, Christopher; Rao, Sriram; Urgo, Kimberly; Prenner, Stuart B.; Wald, Joyce; Atluri, Pavan; Birati, Edo Y.

doi:10.1016/j.cardfail.2020.04.007

Cited by 31 publications

(38 citation statements)

References 4 publications

(3 reference statements)

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“…describe a potential “functionally immunocompromised state” with prior literature demonstrating impaired cellular immunity in long-term LVAD recipients. 3 However, Mahmood et al. describe a net effect of LVAD support which decreases inflammatory cytokines compared to pre-implant levels.…”

Section: Discussionmentioning

confidence: 99%

Management of COVID-19 in a durable left ventricular assist device recipient: A continuity of care perspective

et al. 2020

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COVID-19 is impacting the cardiovascular community both here in the United States and globally. The rapidly emerging cardiac complications have heightened implications for those with underlying cardiovascular disease. We describe an early case of COVID-19 in a left ventricular assist device recipient in the United States. We discuss our clinical management during the initial admission, outpatient management, and a unique complication of this disease over a 40-day disease course.

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Section: Discussionmentioning

confidence: 99%

Management of COVID-19 in a durable left ventricular assist device recipient: A continuity of care perspective

et al. 2020

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“…Gallbladder involvement although rare with SARS-CoV-2 has also been described in the literature [38,39]. One report describes three hospitalized patients who developed acute pain abdomen while recovering from COVID-19 pneumonia.…”

Section: Gall Bladder Involvementmentioning

confidence: 91%

What GI Physicians Need to Know During COVID-19 Pandemic

2020

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The worldwide pandemic of COVID-19, caused by the virus SARS-CoV-2, continues to cause significant morbidity and mortality in both low-and high-income countries. Although COVID-19 is predominantly a respiratory illness, other systems including gastrointestinal (GI) system and liver may be involved because of the ubiquitous nature of ACE-2 receptors in various cell lines that SARS-CoV-2 utilizes to enter host cells. It appears that GI symptoms and liver enzyme abnormalities are common in COVID-19. The involvement of the GI tract and liver correlates with the severity of disease. A minority (10-20%) of patients with COVID-19 may also present initially with only GI complaints. The most common GI symptoms are anorexia, loss of smell, nausea, vomiting, and diarrhea. Viral RNA can be detected in stool in up to 50% of patients, sometimes even after pharyngeal clearance, but it is unclear whether fecal-oral transmission occurs. Liver enzymes are elevated, usually mild (2-3 times), in a substantial proportion of patients. There are many confounding factors that could cause liver enzyme abnormalities including medications, sepsis, and hypoxia. Although infection rates in those with preexisting liver disease are similar to that of general population, once infected, patients with liver disease are more likely to have a more severe disease and a higher mortality. There is a paucity of objective data on the optimal preventive or management strategies, but few recommendations for GI physicians based on circumstantial evidence are discussed.

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“…In peak surges of the pandemic, it may be reasonable to postpone LVAD candidates in Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) stage ≥ 4. [ 22 , 36 , 37 , 38 ].…”

Section: Preoperative Strategies For Cardiac Surgery Patientsmentioning

confidence: 99%

Providing safe perioperative care in cardiac surgery during the COVID-19 pandemic

Mihalj¹,

Mosbahi²,

Schmidli³

et al. 2021

Best Practice & Research Clinical Anaesthesiology

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Novel Coronavirus Disease 2019 in a Patient on Durable Left Ventricular Assist Device Support

Cited by 31 publications

References 4 publications

Management of COVID-19 in a durable left ventricular assist device recipient: A continuity of care perspective

Management of COVID-19 in a durable left ventricular assist device recipient: A continuity of care perspective

What GI Physicians Need to Know During COVID-19 Pandemic

Providing safe perioperative care in cardiac surgery during the COVID-19 pandemic

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