Novel contrast-enhanced ultrasound imaging in prostate cancer

Smeenge, Martijn; Mischi, Massimo; Pes, M. Pilar Laguna; Rosette, Jean J.M.C.H. de la; Wijkstra, Hessel

doi:10.1007/s00345-011-0747-3

Cited by 52 publications

(36 citation statements)

References 32 publications

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“…The preliminary results are promising [ 97 ] ( Fig. 4 ) [ 128 ] , but more extensive validation is still on-going.…”

Section: A B C R U S S O E T a Lmentioning

confidence: 89%

“…This nonlinear behaviour gives rise to several strategies aimed at enhancing the signal refl ected by the UCAs (nonlinear) while suppressing the signal refl ected by tissue (linear) [ 121 ] . Increasing the contrast-totissue ratio in the reconstructed images results in increased sensitivity to UCAs ( Table 1 ) and improved imaging of microvascular perfusion in cancer lesions [ 96,97 ] .…”

Section: Ceusmentioning

confidence: 99%

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Angiogenesis in prostate cancer: onset, progression and imaging

et al. 2012

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What's known on the subject? and What does the study add?Today, angiogenesis is known to play a key role in cancer growth and development. Emerging cancer treatments are based on the suppression of angiogenesis, and modern imaging techniques investigate changes in the microvasculature that are caused by angiogenesis. As for other forms of cancers, angiogenesis is well recognised as a fundamental process in the development of prostate cancer.The novelty of this extensive report on angiogenesis in cancer, with particular attention on prostate cancer and the imaging techniques able to detect it, is the new prospective to the subject. In contrast with the other available reviews, this report goes from ‘theory’ to ‘practice’, establishing a clear link between angiogenesis development and imaged angiogenesis features. Once the key role of angiogenesis in the development of cancer and in particular prostate cancer has been fully described, attention is turned to the current imaging methods with the potential to assess the angiogenesis process and, as a consequence, to detect and localise prostate cancer. As confirmed by all available statistics, cancer represents a major clinical and societal problem in the developed world. The form of cancer with the highest incidence in men is prostate cancer. For prostate cancer, as well as for most forms of cancer, detection of the disease at an early stage is critical to reduce mortality and morbidity. Today, it is well known that pathological angiogenesis represents a crucial step in cancer development and progression. Comparable with most forms of cancer, angiogenesis also plays a fundamental role for prostate cancer growth. As a consequence, angiogenesis is an ideal target not only for novel anti‐angiogenic therapies, but also for modern imaging techniques that aim at cancer localisation by detection of angiogenic microvascular changes. These techniques are mainly based on magnetic resonance, ultrasound, and nuclear imaging. This paper provides a comprehensive review of the available studies on angiogenesis in prostate cancer and its use by modern and emerging imaging techniques for prostate cancer localisation.

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“…The preliminary results are promising [ 97 ] ( Fig. 4 ) [ 128 ] , but more extensive validation is still on-going.…”

Section: A B C R U S S O E T a Lmentioning

confidence: 89%

Section: Ceusmentioning

confidence: 99%

Angiogenesis in prostate cancer: onset, progression and imaging

et al. 2012

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“…It can indicate the spread of cancer in other parts like liver and pancreas. It is also used to diagnose problems of the liver, gallbladder (such as gallstones), pancreas, thyroid gland, lymph nodes, ovaries, prostrate, kidneys, bladder, breast, abnormal widening of blood vessels (aneurysms), cysts and tumors [77,78].…”

Section: Ultrasound (Us)mentioning

confidence: 99%

Advances in Biomedical Imaging and Image Fusion

Chandrashekar¹,

Sreedevi²

2018

IJCA

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Biomedical imaging is a series of procedures which create images of the human body, or parts of the body, to help screen for possible illness or injury, diagnose the likely cause of symptoms and monitor health conditions or the effects of treatment. The objective of the paper is to provide an overview about various bio medical imaging techniques used in detection and diagnosis of Cancer. Each of these imaging techniques provides information about the anatomy, chemical or physiologic phenomena of the human body which are studied independently by doctors to identify Cancer. The biomedical imaging systems, applications, benefits, drawbacks and research challenges are discussed. Image Fusion and its role in Bio medical imaging is also discussed. Image Fusion is the process of fusing two or more bio medical images which contain complementary information into a single composite image. These enrich image quality and avoid redundancy thereby increase the clinical applicability of medical images for cancer detection, prognosis and treatment planning of Cancer.

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“…A large proportion of novel USCAI technologies [7,8] appears to focus on the improvement of PWI imaging quality. Most of these existing methods enhance the image CTR by utilizing the abundant harmonic signals produced by UCAs.…”

Section: Introductionmentioning

confidence: 99%

Contrast-Enhanced Ultrasound Imaging Based on Bubble Region Detection

Huang

Tong

et al. 2017

Applied Sciences

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Abstract:The study of ultrasound contrast agent imaging (USCAI) based on plane waves has recently attracted increasing attention. A series of USCAI techniques have been developed to improve the imaging quality. Most of the existing methods enhance the contrast-to-tissue ratio (CTR) using the time-frequency spectrum differences between the tissue and ultrasound contrast agent (UCA) region. In this paper, a new USCAI method based on bubble region detection was proposed, in which the frequency difference as well as the dissimilarity of tissue and UCA in the spatial domain was taken into account. A bubble wavelet based on the Doinikov model was firstly constructed. Bubble wavelet transformation (BWT) was then applied to strengthen the UCA region and weaken the tissue region. The bubble region was thereafter detected by using the combination of eigenvalue and eigenspace-based coherence factor (ESBCF). The phantom and rabbit in vivo experiment results suggested that our method was capable of suppressing the background interference and strengthening the information of UCA. For the phantom experiment, the imaging CTR was improved by 10.1 dB compared with plane wave imaging based on delay-and-sum (DAS) and by 4.2 dB over imaging based on BWT on average. Furthermore, for the rabbit kidney experiment, the corresponding improvements were 18.0 dB and 3.4 dB, respectively.

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Novel contrast-enhanced ultrasound imaging in prostate cancer

Cited by 52 publications

References 32 publications

Angiogenesis in prostate cancer: onset, progression and imaging

Angiogenesis in prostate cancer: onset, progression and imaging

Advances in Biomedical Imaging and Image Fusion

Contrast-Enhanced Ultrasound Imaging Based on Bubble Region Detection

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