Abstract:Contrast‐enhanced ultrasonography provides a more functional diagnostic image than conventional ultrasonography. This prospective exploratory study compared the novel contrast agent, Visphere™, with commercial contrast agents in five healthy Beagle dogs. Visphere™ has the smallest diameter and highest concentration compared with Sonazoid® and SonoVue®. Each dog received an intravenous injection of Visphere™, Sonazoid®, or SonoVue®. Images were recorded for 300, 600, and 60 s in the heart, liver, and left kidne… Show more
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