Novel concept on in situ syntheses and investigation of photon energy effect on AgNP size with a custom build device for enhanced antimicrobial efficiency

Ultra-stable nano-micro bubbles in a biocompatible medium for safe delivery of anti-cancer drugs

“…AgNPs in the colloidal blend were found using blue LED source. The LED syntheses protocol was previously described in our study 12 . Briefly blend of hybrid colloidal with silver salts was stirred up to a homogenous state and then transferred into a quartz cuvette.…”

“…Additionally, the aqueous blend containing CMC exhibits a generous free space between cross-linked networks during the swollen stage, creating favorable conditions for the nucleation and growth of silver nanoparticles (AgNPs) 47 . The 4.04 eV energy of blue LED is enough to reduces of AgNPs in engineered biocompatible nanocomposite up to size range 4–6 nm in 12 min with functionalized hydroxyl, carboxyl and amide bone sides 12 .…”

“…Furthermore, the functional groups present on the surface of the achieved AgNPs, such as hydroxyl (OH), carboxyl (COO), and amine (−H 2 N) groups (Fig. 2 a) 12 , offer a unique opportunity for both physical and chemical conjugation with highly toxic chemotherapy drugs. Extensive literature highlights a variety of strategies for self-attachment and/or conjugation of modified nanoparticles with toxic chemotherapy drugs like duxorubin, CB7-cisplatin, and CB6-nedaplatin, involving hydrogen bonding, covalent bonding, Amine-carboxyl bonding, hydrophobic interactions, electrostatic interactions, π–π stacking, and van der Waals forces 22 , 31 – 33 .…”