Novel clinico-morphological classification of the corneal endothelial-epithelial dystrophy

Abstract

The article reviews the literature on the classification of endothelial-epithelial dystrophy (EED) of the cornea. The description of endothelial structure, etiology and pathogenesis of the corneal EED are described. Based on own multiple observations and modern methods of corneal tissue imaging, a new modification of the EED classification by V.V. Volkov and M.M. Dronov was created and is presented in the article. This classification makes it possible to more accurately determine the etiopathogenesis of changes in corneal layers and to choose a most rational and effective treatment method. (For citation: Riks IA, Papanyan SS, Astakhov SYu, Novikov SA. Novel clinico-morphological classification of the corneal endothelial-epithelial dystrophy. Ophthalmology Journal. 2017;10(3):46-52. doi: 10.17816/OV10346-52).

CTG18.1 Expansion is the Best Classifier of Late-Onset Fuchs' Corneal Dystrophy Among 10 Biomarkers in a Cohort From the European Part of Russia

“…FECD stage was scored according to the Volkov and Dronov classification (1978). 29 The latter stratifies the disease into 5 stages: I -endothelial (endothelial changes appear as centrally located single or confluent guttae), II -stromal (development of edema in the stroma and corneal epithelium), III -epithelial (bullous), IV -neovascular, and V -terminal (fibrotic). Patients diagnosed with FECD ( ‡45 years old) were included in the FECD group (n ¼ 100).…”