Novel chitin scaffolds derived from marine sponge Ianthella basta for tissue engineering approaches based on human mesenchymal stromal cells: Biocompatibility and cryopreservation

Mesenchymal Cell Growth and Differentiation on a New Biocomposite Material: A Promising Model for Regeneration Therapy

“…These promising findings revealed that the scaffold supports the growth and differentiation of mesenchymal cells that demonstrate their full physiological function with no sign of material toxicity. The cells' functionality performance indicates and suggests that the scaffold is suitable to be developed as a new medical device that has the potential to support regeneration and the production of functional tissue.Biomolecules 2020, 10, 458 2 of 11 new tissue to improves regeneration and healing processes [1,[5][6][7][8][9][10][11]. The use of naturally made scaffolds is the best approach, but they may lack the physical/mechanical properties needed for the new tissue formed.We have developed a composite biomaterial scaffold made from collagen fibers embedded in alginate hydrogel [12][13][14][15][16][17].…”

“…Biomolecules 2020, 10, 458 2 of 11 new tissue to improves regeneration and healing processes [1,[5][6][7][8][9][10][11]. The use of naturally made scaffolds is the best approach, but they may lack the physical/mechanical properties needed for the new tissue formed.…”

Electrochemical method for isolation of chitinous 3D scaffolds from cultivated Aplysina aerophoba marine demosponge and its biomimetic application

“…In recent decades, the synthesis and application of 3D biopolymer-based scaffolds represent one of the new trends in environmental science and technology. Owing to their ability to mimic the patterns of natural structures, excellent biocompatibility, high biodegradability and non-toxicity 3D scaffolds of natural origin find increasing applications in medicine, biotechnology and various interdisciplinary fields including tissue engineering, biomimetics, biocatalysis, adsorption techniques and wastewater treatment [1][2][3][4][5][6][7][8][9][10]. Highly versatile and promising biopolymers such as cellulose, chitin, collagen and their derivatives are more and more frequently used in modern technology [11][12][13][14][15][16].…”

3D Chitin Scaffolds from the Marine Demosponge Aplysina archeri as a Support for Laccase Immobilization and Its Use in the Removal of Pharmaceuticals

“…Thus, demosponges of the order Dictioceratida (also known as commercial bath sponges) [7,8] represent a renewable source of proteinaceous spongin scaffolds which have recently been reported as effective in applications in extreme biomimetics [9][10][11][12], waste treatment [13][14][15][16][17], electrochemistry [18], and enzyme immobilization [19]. Meanwhile, marine demosponges of the order Verongiida have been recognized as a renewable source of uniquely pre-structured 3D chitinous scaffolds [20][21][22][23][24][25][26][27][28] which have found applications in tissue engineering [6,21,[29][30][31][32][33][34], drug release [35], the development of hybrid materials [36][37][38][39][40], and environmental science [41,42]. Chitin of invertebrate origin has previously been studied by researchers in protein immobilization as a matrix for the immobilization of enzymes [43][44][45][46][47][48], including ...…”