Novel Carbon Dots Based on Pseudomonas aeruginosa for High Selectivity Detection of Cr6+ and Bioimaging Both in vitro and in vivo

Abstract

Hexavalent chromium (Cr[Formula: see text]), a heavy metal ion, is widely used in a variety of industries, but it is an environmental pollutant and a recognized human carcinogen. Highly selective quantitative detection of Cr[Formula: see text] is important for environmental pollution monitoring and early disease prevention in humans. In this study, nitrogen-containing carbon quantum dots (N-CQDs) were synthesized by hydrothermal carbonization of Pseudomonas aeruginosa and were found to be efficient detectors of Cr[Formula: see text], with a detection limit (LOD) of 0.23 nmol L[Formula: see text](nM). N-CQDs were detectable in plant leaves and onion cells and successfully stained cell membranes and nuclei. Multi-colored images revealed that in Caenorhabditis elegans, N-CQDs entered the digestive tract through ingestion, spared rapidly throughout the body, and were excreted though the anus within 40 min. Synthesis of fluorescent N-CQDs can be exploited to increase the use and a range of applications of bacterial resources. The study methods and results also provide theoretical guidance for future research into the development of bacterial resources.

Nanotechnology in the Diagnosis and Treatment of Osteomyelitis

“…[71][72][73][74]. Carbon dots, a close cousin of the QD, have been used to identify P. Aeruginosa [75]. Despite these promising results, nanotechnology is not the diagnostic standard of practice for identifying bacterial infection in osteomyelitis.…”

Research Progress of Treatment Technology and Adsorption Materials for Removing Chromate in the Environment

“…The vast majority of chromium-containing waste residues are randomly stacked in the plant after the production process. Because the plant has not conducted anti-seepage treatment in the storage yard, many chromium-containing waste residues stacked in the open air enter the soil and water through rain washing, infiltration, and surface runoff [6,7]. The chromium-containing sewage cause the content of chromate in the local soil and water environment to significantly exceed standard levels.…”