Novel autologous, high concentrated fibrin as advanced hemostatic agent for coronary surgery

Mićović, Slobodan; Everts, Peter A.; Čalija, Branko; Strugarević, Evgenija; Grubor, Nikola; Boricic, Mladen; Lešanović, Jelena; Box, Henk A. M.; Abazović, Džihan

doi:10.1016/j.transci.2021.103171

Cited by 7 publications

(8 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the research that was utilised for the meta-analysis, 8961 CS persons were in the utilised researchers' starting point, 3663 of them were utilising PRP, and 5298 were control. [12][13][14][15][16][17][18][19][20][21][22] PRP had significantly lower SWI, deep SWI, and superficial SWI, compared to control in CS persons. However, when interacting with its values, caution must be taken since a low sample size of some of the nominated researchers was found for the comparisons in the meta-analysis (5 out of 11 <200 persons).…”

Section: Discussionmentioning

confidence: 81%

“…Eleven papers, published between 2005 and 2022, from a total of 1098 linked research that met the inclusion criteria were chosen for the research. [12][13][14][15][16][17][18][19][20][21][22] The consequences of these investigations are accessible in Table 2. 8961 CS persons were in the utilised researchers' starting point, 3663 of them were utilising PRP, and 5298 were control.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

Platelet‐rich plasma influence on the sternal wounds healing: A meta‐analysis

Zhu

Gao

et al. 2023

International Wound Journal

View full text Add to dashboard Cite

A meta‐analysis research was executed to appraise the effect of platelet‐rich plasma (PRP) on sternal wound healing (SWH). Inclusive literature research till April 2023 was done and 1098 interconnected researches were revised. The 11 picked researches, enclosed 8961 cardiac surgery (CS) persons were in the utilised researchers' starting point, 3663 of them were utilising PRP, and 5298 were control. Odds ratio (OR) and 95% confidence intervals (CIs) were utilised to appraise the effect of PRP on the SWH by the dichotomous approach and a fixed or random model. PRP had significantly lower sternal wound infection (SWI) (OR, 0.11; 95% CI, 0.03–0.34, p < 0.001), deep SWI (OR, 0.29; 95% CI, 0.16–0.51, p < 0.001), and superficial SWI (OR, 0.20; 95% CI, 0.13–0.33, p < 0.001), compared to control in CS persons. PRP had significantly lower SWI, deep SWI, and superficial SWI, compared to control in CS persons. However, caution must be taken when interacting with its values since there was a low sample size of some of the nominated research found for the comparisons in the meta‐analysis.

show abstract

Section: Discussionmentioning

confidence: 81%

Section: Resultsmentioning

confidence: 99%

Platelet‐rich plasma influence on the sternal wounds healing: A meta‐analysis

Zhu

Gao

et al. 2023

International Wound Journal

View full text Add to dashboard Cite

show abstract

“…In addition, there are new hemostatic substances that give its effect without depending on coagulation mechanisms (12) . These substances present extrinsic clotting factors when applied and imitates numerous phases of the coagulation process.…”

Section: Figure (1)mentioning

confidence: 99%

The Role of Absorbable Gelatin Sponge (Gel Foam) in Control of Sternal Bleeding during Cardiac Surgery

Elkhouly

Fouad²

2023

The Egyptian Journal of Hospital Medicine

View full text Add to dashboard Cite

show abstract

“…Understanding of the coagulation cascade and the means to produce coagulation factors safely and on a large scale has led to the introduction of novel haemostatic agents that work independently of the coagulation mechanisms [ 30 , 31 ]. These agents introduce extrinsic clotting factors on application and mimic various stages of the coagulation process.…”

Section: Current Haemostatic Agents and Their Clinical Use In Cardiov...mentioning

confidence: 99%

“…Like BioGlue (Cryolife, Kennesaw, GA, USA), this is a tissue glue that polymerises immediately and establishes a firm adhesive bond [ 31 , 58 ]. Two components are dispensed by a double-chambered syringe.…”

Section: Current Haemostatic Agents and Their Clinical Use In Cardiov...mentioning

confidence: 99%

Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends

et al. 2022

View full text Add to dashboard Cite

Intraoperative haemostasis is of paramount importance in the practice of cardiovascular surgery. Over the past 70 years, topical haemostatic methods have advanced significantly and today we deal with various haemostatic agents with different properties and different mechanisms of action. The particularity of coagulation mechanisms after extracorporeal circulation, has encouraged the introduction of new types of topic agents to achieve haemostasis, where conventional methods prove their limits. These products have an important role in cardiac, as well as in vascular, surgery, mainly in major vascular procedures, like aortic dissections and aortic aneurysms. This article presents those agents used for topical application and the mechanism of haemostasis and offers general recommendations for their use in the operating room.

show abstract

Novel autologous, high concentrated fibrin as advanced hemostatic agent for coronary surgery

Cited by 7 publications

References 20 publications

Platelet‐rich plasma influence on the sternal wounds healing: A meta‐analysis

Platelet‐rich plasma influence on the sternal wounds healing: A meta‐analysis

The Role of Absorbable Gelatin Sponge (Gel Foam) in Control of Sternal Bleeding during Cardiac Surgery

Biomaterials as Haemostatic Agents in Cardiovascular Surgery: Review of Current Situation and Future Trends

Contact Info

Product

Resources

About