Novel Approaches to the Diagnosis and Treatment of Frontal Lobe Dysfunction

Goldberg, Elkhonon; Bougakov, Dmitri

doi:10.1007/978-1-4757-5569-5_6

Cited by 5 publications

(3 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The changes in scores on the BRIEF‐A within participants were not as marked as was seen for the neuropsychological assessments. One possible reason for this is the fact that neuropsychological assessments measure EFs over a short period of time and thus may not capture the integrated, multifaceted decisions that form the executive process in real‐life situations (Goldberg and Bougakov ; Burgess, ). These challenges may help to explain why an improvement in an executive process as measured by a neuropsychological assessment may not be seen in a behavioural measure of EF in real‐life situations.…”

Section: Discussionmentioning

confidence: 99%

Examining the effects of computerised cognitive training on levels of executive function in adults with Down syndrome

McGlinchey

McCarron

Holland

et al. 2019

J intellect Disabil Res

View full text Add to dashboard Cite

Background Individuals with Down syndrome (DS) are at much greater risk of developing Alzheimer's disease, and one of the early clinical symptoms of Alzheimer's disease is executive dysfunction. In the general population, cognitive training has shown some promising results in relation to maintaining or improving cognitive processes. There is currently a gap in the literature in relation to cognitive training for adults with DS. Methods A quasi‐experimental mixed factorial design with partial crossover was used involving an 8‐week intervention period using a brain training programme. Participants were matched on age and then randomly assigned to either the intervention group or the delayed intervention group. Forty adults with DS, aged between 30 and 49 and with a mild or moderate level of intellectual disability, participated in the study. All participants completed baseline measures of executive function, using both neuropsychological assessments and an informant‐rated measure of behavioural executive function. The intervention group first completed the training and then the delayed intervention group. Executive function assessments were repeated for both groups following the training. Results The study aimed to examine whether a cognitive training programme could have an effect on levels of executive function. While conclusions are limited owing to small sample size, improvement was seen in neuropsychological assessments of executive function following cognitive training. Positive effects reflected in everyday behaviours were not as promising. Conclusions This study showed that, while it has not been previously an area of focus, individuals with DS can complete a computerised cognitive training programme. Furthermore, the results were promising with significant improvements found in neuropsychological assessments of executive function. These findings need further investigation with a larger sample size and would benefit from the use of a brain imaging component to strengthen the findings.

show abstract

Section: Discussionmentioning

confidence: 99%

Examining the effects of computerised cognitive training on levels of executive function in adults with Down syndrome

McGlinchey

McCarron

Holland

et al. 2019

J intellect Disabil Res

View full text Add to dashboard Cite

show abstract

“…Cavellini, Pagnin, and Vecchi (2003) and Rapp, Brenes, and Marsh (2002), for example, found memory training to benefit both young and older adults. Cognitive training programs described by Ball et al (2002), Goldberg (2005), and Schaie and Willis (1986) have also demonstrated consistent cognitive improvement. These programs should be supported by referrals for vocational rehabilitation.…”

Section: Treatment Implications Of the Casementioning

confidence: 74%

“…The ECB identifies presence and the extent of the "executive dyscontrol" or "frontal lobe" syndrome (Goldberg, 2005;Lamar et al, 1997;Lezak et al, 2004). The four tests in this battery are based on the work of Luria (1962) and include the Graphical Sequences Test, Manual Postures Test, Motor Sequence Test, and Competing Programs Test.…”

Section: Frontal Lobe Executive Functioning and Attentionmentioning

confidence: 99%

A Patient With Bipolar Illness and Her Neuropsychological Signature

Scott

Cleary

2007

Clinical Case Studies

View full text Add to dashboard Cite

This article describes a case study in which neuropsychological assessment was carried out on a 30-year-old, previously diagnosed, bipolar female to determine existence of specific deficits in cognitive function. The patient, whose mood cycles were 12 hours to 24 hours, was subsequently evaluated 8 hours per day for 5 consecutive days (a complete work week of neuropsychological assessment). Neuropsychological results showed motor slowing, right hemispheric dysfunctioning, and memory problems during depressive periods and attentional and executive problems during hypomanic and manic periods. The most normal performance was found during euthymic periods. In addition, left and right hemi visual neglect, aphasia, and sensorimotor problems were present across all mood states. Treatment implications are subsequently described.

show abstract

References

2010

Cognition, Brain, and Consciousness

View full text Add to dashboard Cite

Novel Approaches to the Diagnosis and Treatment of Frontal Lobe Dysfunction

Cited by 5 publications

References 43 publications

Examining the effects of computerised cognitive training on levels of executive function in adults with Down syndrome

Examining the effects of computerised cognitive training on levels of executive function in adults with Down syndrome

A Patient With Bipolar Illness and Her Neuropsychological Signature

References

Contact Info

Product

Resources

About