Novel Approaches to Imaging Brain Tumors

High-Pass-Filtered Phase Image: Left- versus Right-Handed MR Imaging Systems

“…3 The article showed that high-pass-filtered phase images can depict intratumoral calcification in oligodendrogliomas better than conventional MR images; this finding has been reported before. 4 Understanding the contrast appearance of high-passfiltered phase images on left-handed versus right-handed MR imaging systems would make distinguishing diamagnetic calcification from paramagnetic hemorrhage a much easier task and prevent any possible confusion.…”

“…This description is true, but only in the case of right-handed MR imaging systems, while in left-handed MR imaging systems, the complete opposite signal would be seen: Paramagnetic substances would appear bright, while diamagnetic substances would appear dark. 2,3 In Figs 2D and 3D of the above-mentioned article, the highpass-filtered phase images are those of a left-handed MR imaging system, evident by the bright signal of the veins (paramagnetic deoxyhemoglobin).…”

An attempt toward objective assessment of brain tumor vascularization using susceptibility weighted imaging and dedicated computer program – a preliminary study

“…Therefore, this technique can be used in non-invasive and non-contrast-enhanced visualization of vascular structures, hemorrhages and iron depositions that are not well visible in other MRI sequences. Usefulness of SWI was confirmed in the diagnosis of wide variety of intracranial pathologies such as vascular malformations, cerebrovascular disease, trauma and neurode-generative disorders [5–8]. Furthermore, SWI is a promising sequence for tumor imaging as it could be used to characterize lesions by discriminating blood products and venous vasculature and visualizing its internal architecture.…”