Novel Antifouling and Antimicrobial Compound from a Marine-Derived Fungus Ampelomyces sp.

Kwong, Theresa; Miao, Li; Li, Xiancui; Qian, Pei‐Yuan

doi:10.1007/s10126-005-6146-2

Cited by 67 publications

(30 citation statements)

References 16 publications

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“…The fungus Ampelomyces sp. produced 3-chloro-2,5-dihydroxybenzyl alcohol, which inhibited not only the growth of marine bacterial species, but also prevented settlement of Hydroides elegans and larvae of Balanus amphitrite (Kwong et al 2006). The fungus Aspergillus sp.…”

Section: Fungimentioning

confidence: 99%

Mini-review: Inhibition of biofouling by marine microorganisms

2013

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Any natural or artificial substratum exposed to seawater is quickly fouled by marine microorganisms and later by macrofouling species. Microfouling organisms on the surface of a substratum form heterogenic biofilms, which are composed of multiple species of heterotrophic bacteria, cyanobacteria, diatoms, protozoa and fungi. Biofilms on artificial structures create serious problems for industries worldwide, with effects including an increase in drag force and metal corrosion as well as a reduction in heat transfer efficiency. Additionally, microorganisms produce chemical compounds that may induce or inhibit settlement and growth of other fouling organisms. Since the last review by the first author on inhibition of biofouling by marine microbes in 2006, significant progress has been made in the field. Several antimicrobial, antialgal and antilarval compounds have been isolated from heterotrophic marine bacteria, cyanobacteria and fungi. Some of these compounds have multiple bioactivities. Microorganisms are able to disrupt biofilms by inhibition of bacterial signalling and production of enzymes that degrade bacterial signals and polymers. Epibiotic microorganisms associated with marine algae and invertebrates have a high antifouling (AF) potential, which can be used to solve biofouling problems in industry. However, more information about the production of AF compounds by marine microorganisms in situ and their mechanisms of action needs to be obtained. This review focuses on the AF activity of marine heterotrophic bacteria, cyanobacteria and fungi and covers publications from 2006 up to the end of 2012.

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Section: Fungimentioning

confidence: 99%

Mini-review: Inhibition of biofouling by marine microorganisms

2013

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“…Some marine organisms produce cyclopeptides, 3 and the compounds have shown promise for several pharmaceutical and other applications. [4][5][6][7] The rigid central ring limits conformational freedom, 7 making them tractable models of larger peptides. 3 We note that the adsorption of peptides on surfaces is a subject of wide current interest, and this includes dipeptides: [8][9][10] to investigate them in the condensed state, it is of great help to have reference data for the isolated molecules.…”

Section: Introductionmentioning

confidence: 99%

Photoelectron spectra and structures of three cyclic dipeptides: PhePhe, TyrPro, and HisGly

Arachchilage

Wang

Feyer

et al. 2012

The Journal of Chemical Physics

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We have investigated the electronic structure of three cyclic dipeptides: cyclo(Histidyl-Glycyl) (cHisGly), cyclo(Tyrosyl-Prolyl) (cTyrPro), and cyclo(Phenylalanyl-Phenylalanyl) (cPhePhe) in the vapor phase, by means of photoemission spectroscopy and theoretical modeling. The last compound was evaporated from the solid linear dipeptide, but cyclised, losing water to form cPhePhe in the gas phase. The results are compared with our previous studies of three other cyclopeptides. Experimental valence and core level spectra have been interpreted in the light of calculations to identify the basic chemical properties associated with the central diketopiperazine ring, and with the additional functional groups. The valence spectra are generally characterized by a restricted set of outer valence orbitals separated by a gap from most other valence orbitals. The theoretically simulated core and valence spectra of all three cyclic dipeptides agree reasonably well with the experimental spectra. The central ring and the side chains act as independent chromophores whose spectra do not influence one another, except for prolyl dipeptides, where the pyrrole ring is fused with the central ring. In this case, significant changes in the valence and core level spectra were observed, and explained by stronger hybridization of the valence orbitals.

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“…So far, only a limited number of phylogenetic clades of marine bacteria and fungi have been screened for their antifouling activity [12,16]. This study evaluated the bioactivity of some never-before-examined marine bacteria and was able to successfully and systematically pool out and identify at least 50% of these sponge-associated novel marine bacteria as having good antifouling potential.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial and antilarval-settlement potential and metabolite profiles of novel sponge-associated marine bacteria

Dash

Jin

Lee

et al. 2009

J Ind Microbiol Biotechnol

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In this study, we screened seven novel sponge-associated marine bacteria for their antibacterial and antilarval-settlement activity in order to find possible new sources of non-toxic or less toxic bioactive antifoulants. The anti-bacterial-growth activity of crude extracts of each bacterium was evaluated by the disk-diffusion assay. Extracts of four potent bacteria with high and broad spectra of antibacterial activity were further separated with solvents of different polarities (hexane and ethyl acetate). To evaluate their indirect inhibitive effect on larval settlement, we tested for their antibiofilm formation activity against two of the test bacteria (Vibrio halioticoli and Loktanella hongkongensis) inductive to Hydroides elegans larval settlement. About 60 and 87% of the extracts inhibited biofilm formation by V. halioticoli and by L. hongkongensis respectively. The extracts were also tested for their direct antilarval-settlement activity against the barnacle Balanus amphitrite and the polychaete H. elegans; 87% of the extracts had a strong inhibitive effect on larval settlement of both species. Extracts of two of the isolates completely inhibited larval settlement of B. amphitrite at 70 microg ml(-1) and H. elegans at 60 microg ml(-1). The organic extracts of Winogradskyella poriferorum effectively inhibited the larval settlement of both H. elegans and B. amphitrite and the biofilm formation of the two bacterial species. The metabolites present in the active crude extracts were profiled using GC MS, and the most prevalent metabolites present in all extracts were identified. This study successfully identified potential new sources of antifouling compounds.

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Novel Antifouling and Antimicrobial Compound from a Marine-Derived Fungus Ampelomyces sp.

Cited by 67 publications

References 16 publications

Mini-review: Inhibition of biofouling by marine microorganisms

Mini-review: Inhibition of biofouling by marine microorganisms

Photoelectron spectra and structures of three cyclic dipeptides: PhePhe, TyrPro, and HisGly

Antibacterial and antilarval-settlement potential and metabolite profiles of novel sponge-associated marine bacteria

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