Novel Anti-Oxidant V2O5 Nanowires Prevent Spine Loss in Primary Cortical Neurons Derived from a Mouse Model of Alzheimer′s Disease

Das, Debajyoti; Ghosh, Satadal; Vernekar, Amit A.; Mugesh, Govindasamy; Ravindranath, Vijayalakshmi

doi:10.1016/j.freeradbiomed.2016.10.418

Cited by 1 publication

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This ROS reduction mechanism has proven to be beneficial in reversing the impairments observed in primary cortical neurons of mice with APP/PS1 mutations. [ 243 ] These findings reveal that the ability of V 2 O 5 nanowires to catalyze peroxidase activity makes them candidate drugs for the treatment of AD.…”

Section: Low‐dimensional Nanomaterials For Alzheimer's Disease Treatmentmentioning

confidence: 99%

Alzheimer's Disease: Status of Low‐Dimensional Nanotherapeutic Materials

Huang,

Liao,

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease that constitutes the third most common cause of death among elderly individuals. AD patients suffer from behavioral problems regularly, like memory loss, thinking deficits, and cognitive disorders. Currently, the incidence rate of AD has been on the rise worldwide. Therefore, it is imperative to develop effective strategies for the treatment and prevention of AD. The inherent characteristics of low‐dimensional nanomaterials, primarily their smaller size and surface structure, make them well‐suited for fulfilling the essential requirements of therapeutic drug design. Consequently, these nanomaterials offer a highly appealing and alternative approach to treating AD. Here, the low‐dimensional nanomaterials used in the treatment of AD to provide new ideas, methods, and comprehensive perspectives for the management of AD are reviewed. This review will advance the comprehensive understanding of the potential of low‐dimensional nanomaterials in the field of neuro medicine, which also will have a positive impact on future research.

show abstract

Section: Low‐dimensional Nanomaterials For Alzheimer's Disease Treatmentmentioning

confidence: 99%