Novel and Direct Nucleophilic Sulfenylation and Thiocyanation of Phenol Ethers Using a Hypervalent Iodine(III) Reagent

Synthesis and biological activity of sulfur compounds showing structural analogy with combretastatin A-4

“…The sulfoxides and sulfones were obtained at a high yield by oxidation of sulfides with m -CPBA. 13 The preparation of compounds 10 and 16 was reported in the literature, 14–16 but neither of the compounds were synthesized by the procedures described here, nor were they examined for potential cytotoxic and antitubulin activities. The structure of all compounds was confirmed by spectroscopic methods.…”

A Simple, Convenient One‐Pot Synthesis of Dithio‐Carbamide Derivatives of Heterocyclic 1,3‐Dicarbonyl Systems

“…The sulfenylation of aryl compounds is an important issue in synthetic organic chemistry . Nonactivated aromatic compounds can be sulfenylated by using electrophiles of disulfides in presence of Lewis acid catalysis (for instance SbCl 5 /AgSbF 6 ) .…”

Green Thiocyanation of Aromatic and Heteroaromatic Compounds by Using Silica Boron Sulfonic Acid as a New Catalyst and H<SUB>2</SUB>O<SUB>2</SUB> as Mild Oxidant

“…In view of the versatility of thiocyanate group in heterocyclic construction [8], it will be of significance to probe the thiocyanation of aromatic and heteroaromatic compounds. Several methods have been developed for the thiocyanation of arenes by using various reagents under certain conditions [9][10][11][12][13][14][15][16][17][18]. Yet, only a limited number of reagents, such as bromine/potassium thiocyanate (only for indoles) [15], N-thiocyanatosuccinimide (only for 5-methoxy-2-methylindole and accompanied by two bisthiocyanates) [16], ceric ammonium nitrate (CAN) [17], acidic mont K10 clay [18], iodine/methanol, oxone [19], diethyl azodicarboxylate [20], IL-OPPh2 [21], potassium peroxydisulfate-copper(II) [22], have been applied to the thiocyanation of aromatic and heteroaromatic systems.…”