Abstract:This study presents a novel multifunctional probe Gd-EB-ICG based on albumin-binding for synergistic enhancement of fluorescence (FL) and magnetic resonance (MR) imaging-guided photothermal cancer therapy. In vitro experiments demonstrated that Gd-EB-ICG exhibits superior fluorescence intensity, longitudinal relaxivity, and photothermal conversion efficiency. In vivo experiments demonstrated that Gd-EB-ICG exhibits excellent tumor aggregation, imaging, and killing effects. This simple and feasible strategy suc… Show more
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