Nouvelle technique d'exploration fonctionnelle cérébrale : Le captage centimétrique ultrasonore de la pulsatilité cérébraleApplication au diagnostic des tumeurs intra-crâniennes

Lepetit, J M; Chanchole, S; Dany, A; Ravon, R; Bokor, J; Pefferkorn, J P

doi:10.1016/s0370-4475(76)80041-x

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“…In fact, after the identification of ultrasounds and use of echoencephalography in 1956 by L. Leksell [ 9 ], numerous international scientific publications have confirmed the existence of a spontaneous natural cerebral pulsatility that is synchronous with cardiac systoles [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ].…”

Section: Scientific Backgroundmentioning

confidence: 99%

“…This technique was originally developed in France mostly by J.M. Lepetit [ 18 , 19 , 20 , 21 ] who worked in the 1970s and 1980s in the Neurological Functional Exploration Laboratory at the Dupuytren University Hospital in Limoges, France, where the first echotomoencephalograph or tomosphygmograph was built. As underlined above, the originality of UCTS compared to classical pulsatile echoencephalography is that measurement and recording of the cerebral pulsations take place in different tissue regions of the temporal lobes, making it possible to locate precisely these pulsations in the different neuronal structures within these lobes, resulting in a fundamentally more sensitive and precise method for monitoring neuronal functions and capillary hemodynamics in brain tissue.…”

Section: What Is Ucts?mentioning

confidence: 99%

“…Thus, during unilateral carotid compression, the ipsilateral side has a temporary cessation of pulsatility in the territories corresponding to Centimeters 3–7, which suggests that these territories depend on the carotid system, whereas pulsatile activity persists in the territories corresponding to Centimeters 8 and 9, which suggests that these territories do not depend on this vascular system [ 20 , 21 , 26 ]. By contrast, during a disease-associated or traumatic attack of the vertebral arteries, whatever the cause, inducing its insufficient blood flow, there is a pulsatility collapse in these territories, which suggests that the territories corresponding to Centimeters 8 and 9 depend on the vertebro-basilar artery system [ 28 ].…”

Section: Search For Correspondence Between the Anatomical Regions mentioning

confidence: 99%

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Technical Assessment of Ultrasonic Cerebral Tomosphygmography and New Scientific Evaluation of Its Clinical Interest for the Diagnosis of Electrohypersensitivity and Multiple Chemical Sensitivity

Greco

2020

Diagnostics

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Ultrasonic cerebral tomosphygmography (UCTS), also known as “encephaloscan”, is an ultrasound-based pulsatile echoencephalography for both functional and anatomical brain imaging investigations. Compared to classical imaging, UCTS makes it possible to locate precisely the spontaneous brain tissue pulsations that occur naturally in temporal lobes. Scientific publications have recently validated the scientific interest of UCTS technique but clinical use and industrial development of this ancient brain imaging technique has been stopped notably in France, not for scientific or technical reasons but due to a lack of financing support. UCTS should be fundamentally distinguished from transcranial Doppler ultrasonography (TDU), which, although it also uses pulsed ultrasounds, aims at studying the velocity of blood flow (hemodynamics) in the cerebral arteries by using Doppler effect, especially in the middle cerebral artery of both hemispheres. Instead, UCTS has the technical advantage of measuring and locating spontaneous brain tissue pulsations in temporal lobes. Recent scientific work has shown the possibility to make an objective diagnosis of electrohypersensitivity (EHS) and multiple chemical sensitivity (MCS) by using UCTS, in conjunction with TDU investigation and the detection of several biomarkers in the peripheral blood and urine of the patients. In this paper, we independently confirm the clinical interest of using UCTS for the diagnosis of EHS and MCS. Moreover, it has been shown that repetitive use of UCTS in EHS and/or MCS patients can contribute to the objective assessment of their therapeutic follow-up. Since classical CT scan and MRI are usually not contributive for the diagnosis and are poorly tolerated by these patients, UCTS should therefore be considered as one of the best imaging technique to be used for the diagnosis of these new disorders and the follow-up of patients.

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Section: Scientific Backgroundmentioning

confidence: 99%

Section: What Is Ucts?mentioning

confidence: 99%

Section: Search For Correspondence Between the Anatomical Regions mentioning

confidence: 99%

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Technical Assessment of Ultrasonic Cerebral Tomosphygmography and New Scientific Evaluation of Its Clinical Interest for the Diagnosis of Electrohypersensitivity and Multiple Chemical Sensitivity

Greco

2020

Diagnostics

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Nouvelle technique d'exploration fonctionnelle cérébrale : Le captage centimétrique ultrasonore de la pulsatilité cérébraleApplication au diagnostic des tumeurs intra-crâniennes

Cited by 1 publication

References 1 publication

Technical Assessment of Ultrasonic Cerebral Tomosphygmography and New Scientific Evaluation of Its Clinical Interest for the Diagnosis of Electrohypersensitivity and Multiple Chemical Sensitivity

Technical Assessment of Ultrasonic Cerebral Tomosphygmography and New Scientific Evaluation of Its Clinical Interest for the Diagnosis of Electrohypersensitivity and Multiple Chemical Sensitivity

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