Nouveaux tests pour le diagnostic de la tuberculose

Ninet, Béatrice Alice Bescher; Roux‐Lombard, Pascale; Schrenzel, Jacques; Janssens, Jean–Paul

doi:10.1016/j.rmr.2010.12.012

Cited by 10 publications

(5 citation statements)

References 57 publications

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“…In fine, cette stratégie devrait permettre de supprimer le protocole de retraitement. Dans la situation actuelle, certains cas de TB sont « surtraités » par le retraitement en absence de test de résistance, parce qu'à bacilles sensibles, d'autres des cas de TB sont « sous-traités » par le protocole de retraitement parce qu'à bacilles MR. Les avantages des tests de diagnostic de la résistance sont énormes : diagnostic rapide de la TB-MR [16], rupture de la transmission de bacilles MR, optimisation des moyens de traitement avec les baisses certaines des coûts de commandes, guérison des patients avec le moins possible de séquelles respiratoires.…”

Section: Discussionunclassified

Profil clinique, microbiologique et évolutif des patients en situation d’échecs et de rechutes de tuberculose en Côte d’Ivoire

Kouamé-N’Takpé¹,

Horo

Koné

et al. 2015

Revue de Pneumologie Clinique

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Section: Discussionunclassified

Profil clinique, microbiologique et évolutif des patients en situation d’échecs et de rechutes de tuberculose en Côte d’Ivoire

Kouamé-N’Takpé¹,

Horo

Koné

et al. 2015

Revue de Pneumologie Clinique

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“…Microbiological tests confirm the clinical diagnosis. Microscopic examination after ZN staining remains the most accessible and least expensive examination in semi-urban areas, with a more or less acceptable sensitivity [12]. Compared to the result of Horo et al [18] who found a sensitivity of 85% with respect to the reference test, which is the culture.…”

Section: Microscopy and Xpert Mtb/rif ® Testingmentioning

confidence: 99%

“…Indeed, microscopy often gives false negative results while the culture of mycobacteria takes too long. These limitations have favoured molecular diagnostic methods, such as the Xpert MTB/RIF ® test, which nowadays plays an important role in the diagnosis of the disease [11][12]. Early diagnosis is essential in order to reduce the delay in starting treatment and the high mortality caused by delays in treatment.…”

Section: Introductionmentioning

confidence: 99%

Contribution of XPERT MTB/RIF® in the diagnosis of pulmonary tuberculosis in Ziguinchor, Senegal

Sarr

Niang

Dieye

et al. 2020

Microbes and Infectious Diseases

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Background: Multidrug-resistant tuberculosis (MDR-TB) is resistant to isoniazid and rifampicin. It is favored by poverty and infection with the human immunodeficiency virus. This retrospective, descriptive study aimed to determine the contribution of Xpert MTB/RIF® in the diagnosis of multidrug-resistant pulmonary tuberculosis in a semiurban environment at the Peace Hospital of Ziguinchor in Senegal during the period from April 2015 to August 2019. Methods: The study is retrospective, descriptive and carried out in the laboratory of Ziguinchor Hospital de la Paix, in southern Senegal, from April 2015 to August 2019. All respiratory specimens were subjected to Ziehl-Neelsen (ZN) stained smear microscopy and Xpert MTB/RIF® testing. Results: 180 samples, i.e. 6.4% were microscopy-negative but positive in Xpert MTB/RIF ® testing. Thirty_two (32) patients (1%) are infected with rifampicin-resistant Mycobacterium tuberculosis (M. tuberculosis), against 29% of patients (798/2794) infected with susceptible strains. Conclusion: Tuberculosis is no longer a "disease of the past". Having a high cost, Xpert MTB/RIF ® testing must be associated with microscopy, which remains accessible in semiurban areas and easy to perform.

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“…They appear flat, small (1 to 2 mm), smooth, white and shiny. The Polymerase Chain Reaction (PCR) new diagnostic methods allows the rapid highlighting of Mycobacterium in an average of 48-72 hours, and quickly identify the different species in the Mycobacterium Tuberculosis complex [12,13]. In our case, the identification of M. Bovis was performed after culture on Löwenstein-Jensen solid medium and phenotypic study.…”

Section: Observationmentioning

confidence: 98%

Coxofemoral Arthritis Caused by Mycobacterium Bovis after Bacillus Calmette-Guérin Therapy

Bouchentouf¹

2015

Clin Med Rev Case Rep

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normocytic normochromic anemia with a 10 g/dl Hb, normal leukocyte count, 30 mm erythrocyte sedimentation rate (ESR) in the first hour and a 25 mg/l CRP. Renal and hepatic biological assessments were normal. The tuberculin skin test was positive at 10 mm and HIV status was negative. Right hip and pelvis radiographs showed a narrowing coxo-femoral joint space with demineralization and geodes of the femoral head (Figure 1).Pelvic CT scan showed an asymmetric basin, with the loss of the right femoral head sphericity and ankylosis of the coxo-femoral space with infiltration of the periarticular soft tissue (Figure 2). The search for germs in the joint fluid was negative on direct examination and the histological study of the synovial performed after a CT guided biopsy showed an epitheloid giant cell granuloma with caseous necrosis suggestive of coxo-femoral tuberculosis (Figure 3). Chest X-ray showed no abnormality and Koch bacillus research

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Nouveaux tests pour le diagnostic de la tuberculose

Cited by 10 publications

References 57 publications

Profil clinique, microbiologique et évolutif des patients en situation d’échecs et de rechutes de tuberculose en Côte d’Ivoire

Profil clinique, microbiologique et évolutif des patients en situation d’échecs et de rechutes de tuberculose en Côte d’Ivoire

Contribution of XPERT MTB/RIF® in the diagnosis of pulmonary tuberculosis in Ziguinchor, Senegal

Coxofemoral Arthritis Caused by Mycobacterium Bovis after Bacillus Calmette-Guérin Therapy

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