Nourishing yin method using herbal medicine for skin disease: A systematic review and meta-analysis

Jun, Ji Hee; Lee, Ju Ah; Roh, Seok-Seon; Choi, Jiae; Choi, Tae Young; Kim, Byung-Hyun; Roh, Hyo Sun; Jin, Mu Hyun; Hwang, Seung Jin; Choi, In-Hwa; Kim, Hyung-Min; Lee, Myeong Soo

doi:10.1016/j.eujim.2017.03.008

Cited by 2 publications

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“…[ 14 ] In addition, Rehmanniae Radix Crudus is prescribed to eliminate pathogenic heat from the blood, and Saposhnikoviae Radix is prescribed to relieve exterior syndrome by dispersion; these are among the most frequently used herbs in nourishing yin treatment for skin disease. [ 15 ] Interestingly, the PASI of both patients increased at 1 month after treatment began, but decreased with continued treatment. We speculate that this was a result of the rebound phenomenon after discontinuation of steroids, [ 16 ] and the process of dispelling heat.…”

Section: Discussionmentioning

confidence: 99%

Effect of Korean medicine as add-on therapy to phototherapy for psoriasis

et al. 2019

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Rationale:Psoriasis is a common chronic, immune-mediated inflammatory skin disease. Here, we describe 2 patients who presented with psoriasis to illustrate the potential efficacy of Korean medicine treatment combined with phototherapy.Patient concerns:A 33-year-old female (Case 1) and a 37-year-old male (Case 2) presented at the clinic with symptoms of itching, erythema, and scaliness.Diagnosis:Both patients were diagnosed with psoriasis based on the locations of erythema, as well as the appearance of circumscribed scaly papules and plaques.Interventions:Patients underwent 5 months (Case 1) and 8 months (Case 2) of treatments with acupuncture, herbal medicine, probiotics, and phototherapy.Outcomes:After treatment, the patients improved in Psoriasis Area and Severity Index score from 7 to 1.2 (Case 1), and 23.2 to 2.2 (Case 2).Lessons:These outcomes suggest that Korean medicine therapies combined with phototherapy may be effective for resolution of psoriasis; however, further research is needed to confirm these findings.

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Section: Discussionmentioning

confidence: 99%

Effect of Korean medicine as add-on therapy to phototherapy for psoriasis

et al. 2019

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“…This improvement is accompanied by the expression of the cytokine LI-4 [ 13 , 14 ]. A recent publication also reported that herbal medicine was favorable for treating BD, showing the potential of herbal medicine in complementing conventional medication [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

Integrative Medicine (Herbal Medicine Combined with Drug Therapy) for Behcet’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

et al. 2021

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This review aimed to investigate the efficacy of integrative medicine (herbal medicine combined with drug therapy) in the treatment of Behcet’s disease (BD). Eleven databases were searched from their inception to 7 December 2020, for randomized control trials (RCTs) that reported the effects of integrative medicine in treating BD. The risk of bias was assessed using seven domain criteria from the Cochrane Collaboration tool. Grading of Recommendations Assessment, Development, and Evaluation (GRADE) was used to assess the quality of evidence. The direction of the effect is also shown in the form of an albatross plot. Sixteen trials met the inclusion criteria and were analyzed. The overall risk of bias was determined to be uncertain. The meta-analysis showed a superior response rate with herbal medicine plus drug therapy (relative risk (RR) 1.19, 95% confidence interval (CI) 1.13 to 1.25, n = 1034, p < 0.00001, I2 = 0%, low certainty of evidence (CoE)) compared to drug therapy. Integrative medicine also lowered the recurrence rate after 2 months of follow-up (RR 0.27, 95% CI 0.09 to 0.76, n = 120, p = 0.01, I2 = 0%, low CoE). The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level, and skin lesions were also significantly improved using integrative medicine, but equivalent effects were seen for oral ulcers, genital ulcers, and eye inflammation. Minor adverse events were reported in both groups. Our findings suggest that herbal medicine combined with drug therapy is more effective for the treatment of BD than drug therapy alone. Although the type of drug therapy used varied across the studies, integrative medicine was shown to improve the total response rate, skin lesions, the ESR, and the CRP level. However, the overall risk of bias of the studies was concerning, and the CoE was low. Information on adverse events (AEs) was also insufficient. In addition, the number of studies included for data synthesis for most outcomes was small. Future studies with rigorous RCTs may help establish the efficacy of integrative medicine in the treatment of BD.

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Nourishing yin method using herbal medicine for skin disease: A systematic review and meta-analysis

Cited by 2 publications

References 3 publications

Effect of Korean medicine as add-on therapy to phototherapy for psoriasis

Effect of Korean medicine as add-on therapy to phototherapy for psoriasis

Integrative Medicine (Herbal Medicine Combined with Drug Therapy) for Behcet’s Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

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