NOTTO transplant specific guidelines with reference to COVID-19

Kute, Vivek B.; Guleria, Sandeep; Prakash, Jai; Shroff, Sunil; Prasad, Narayan; Agarwal, Sanjay Kumar; Varughese, Santosh; Gupta, Subhash; Gokhale, Ashish; Sahay, Manisha; Sharma, Ashish; Varma, Prem; Bhalla, Anil Kumar; Vardhan, Harsh; Balwani, Manish R; Dave, Shruti D; Bhadauria, Dhamendra; Rathi, Manish; Agarwal, Dhananjay; Shah, Pankaj; Ramesh, Vasanthi; Garg, Rajiv

doi:10.4103/ijn.ijn_299_20

Cited by 23 publications

(14 citation statements)

References 7 publications

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“…All the doctors and HCW involved underwent routine preliminary clinical and epidemiological daily checkups for COVID-19. In a nutshell, all the transplantation activity carried out in the COVID-19 era was conducted as per the national guidelines [15] for transplantation. The authors also have previously documented the protocol for donor-recipient management in COVID-19 recovered donors [16] and recipients [17] in the context of living related transplantation.…”

Section: Methodsmentioning

confidence: 99%

Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplantation? A Multicenter Comparative Analysis from India

Meshram

Kute

Patel

et al. 2021

Transplantation Proceedings

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Introduction: Limited data exists on the incidence and outcome of early coronavirus disease (COVID-19) in kidney transplantation recipients (KTR). Methods: A retrospective multicentre research was conducted across 12 centers of India. We explored the symptomatology, demographic, laboratory findings and outcome of COVID-19 within 30 days of transplantation. The outcome was compared with the overall KTR and waitlisted patients acquiring COVID-19. Results: The incidence of early COVID-19 was 2.6% (n =22) for the cumulative 838 renal transplants performed since nationwide lockdown in March 2020 till May 2021. Overall, 1049 KTR were diagnosed with COVID-19 and 2% of those had early COVID-19. The median age of the early COVID-19 cohort was 43(31-46) years. COVID-19 severity ranged from asymptomatic (18.2%), mild (59.1%), moderate (9.1%) and severe (13.6%). Among clinical symptoms, Dyspnea and Anosmia were frequent and in laboratory parameters neutrophil lymphocyte ratio, high sensitive C reactive protein and D- dimer were higher in patients requiring oxygen. The mortality in early COVID-19 was not higher than overall KTR (4.5% vs 8.5%; p-value: 1). COVID-19 severity (23.9% vs 15.7%; p-value: 0.0001) and mortality (15.5% vs 8.5%; p-value: 0.001) among waitlisted patients (n = 1703) were higher compared to overall KTR. Conclusion: We report higher burden of COVID-19 in waitlisted patients compared to KTR and a favorable outcome in early COVID-19 in KTR. Our report will help the transplant physicians in dealing with the ongoing dilemma of halting or resuming transplantation in the COVID-19 era.

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Section: Methodsmentioning

confidence: 99%

Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplantation? A Multicenter Comparative Analysis from India

Meshram

Kute

Patel

et al. 2021

Transplantation Proceedings

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“…[18]. A number of related reviews were reported by Patel et al [17], Singh et al [18], Singh et al [19] and Arora et al [20].…”

Section: What Other Steps Should a Healthmentioning

confidence: 96%

Risk & Hazards of COVID 19 Pandemic on Occupational Professionals

Bonde

Kulkarni

Naqvi

2021

JPRI

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Coronavirus outbreak 2019 causes health-care employees an occupational safety concern. Several thousand health-care workers have been contaminated already. There are various reasons where, various occupational individual expose to the various types of the infections in the surrounding. The infections then have chances to spread in the community via these professionals. World Health Organization therefore has developed some of the Ideal precautionary measures to tackle or overcome this kind of the spreading of such infections. Therefore it is a concern to avoid intra-hospital spread of the communicable disease. Based on the Patient Safety Model Systems Technology Framework, approaches and interventions to protect healthcare workers in an emergency tertiary hospital are defined. In the fields of job activities, technology and equipment, environmental causes of job and organizational conditions. Faced with a possible pandemic, the concept of zero workplace infection remains an ambitious target that all health-care programs must aspire for. Various Technology and Equipment are therefore mandatory to provide to health care individuals, such as, Face mask, Hand gloves, face shield, Personal Protection Kit (PPE), hand sanitizers etc. Also awareness talks from the health care professionals are podcasted in different radio channels, news stations are continuously been published, Also the hospital waste management has primary role to dump out the hospital waste at given professional manner.

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“…Antiinflammatory, anti-oxidants medicines or tablets such supplements of Vitamin C, Vitamin D, probiotic can be advised to take as a prophylactics in order to ward off the disease but strictly under medical supervision. Balance diet and adequate exercise is also able to act as potential prophylactics in if followed properly [13][14][15][16][17][18][19][20][21][22].…”

Section: Prophylactics For Covid-19mentioning

confidence: 99%

Role of Drugs in COVID 19 Patient: A Review

Bhatia

2021

JPRI

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Background: No specific drug treatment is available for the COVID-19. Various drugs are being used and repurposed as COVID-19 treatment. Summary: COVID-19 has no defined treatment course because it has no precedent. Various drugs are tried and tested to be used upon patients to treat particular symptom. Hydroxycholoroquine, lopinavir, ritonavir and so on are the famous drugs being repurposed as COVID-19 treatment drugs. Prophylactics are not widely listed but supplements and drugs which contain anti-inflammatory properties and anti-oxidants should be inculcated in the diet so that innate immune response can fight off the external pathogenic invasion all by itself. Conclusion: Drugs listed for repurposing method must be tried and tested before administered it to a severely ill patients or to a large chunk of population. Proper study needs to be done before administered and starting full-fledged usage of any existing drug not meant for the treatment of COVID-19.

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NOTTO transplant specific guidelines with reference to COVID-19

Cited by 23 publications

References 7 publications

Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplantation? A Multicenter Comparative Analysis from India

Is Early COVID-19 in Kidney Transplant Recipients Concerning Enough to Halt Transplantation? A Multicenter Comparative Analysis from India

Risk & Hazards of COVID 19 Pandemic on Occupational Professionals

Role of Drugs in COVID 19 Patient: A Review

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