Notkun ósæðardælu við kransæðahjáveituaðgerðir

Gunnarsdottir, Sunna Lu Xi; Gunnarsdottir, Erla Liu Ting; Heimisdottir, Alexandra Aldis; Heidarsdottir, Sunna Run; Helgadóttir, Sólveig; Sigurdsson, Martin I.; Guðbjartsson, Tómas

doi:10.17992/lbl.2020.02.372

Cited by 1 publication

(1 citation statement)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Þessum breytum hefur áður verið lýst ítar- lega í nokkrum vísindagreinum í Laeknablaðinu. 19,20 Þar koma meðal annars fram lýðfraeðilegar upplýsingar um kyn og aldur, líkamsþyngdarstuðull (body mass index, BMI), en áhaettuþaettir kransaeðasjúkdóms einnig skráðir, notkun hjarta-og blóðþynningarlyfja auk fyrri sögu um hjarta-og aeðasjúkdóma. Úr aðgerðalýsingum voru skráðar upplýsingar um lengd aðgerðar (skin-to-skin) í mínútum en líka tangar-og vélartími, fjöldi fjaraeðatenginga og tegund aeðagraeðlinga.…”

Section: Klínískar Breyturunclassified

Incidence and outcomes of perioperative myocardial infarction associated with coronary artery bypass surgery

Heiðarsdóttir,

Heitmann,

Gunnarsdottir

et al. 2024

LBL

View full text Add to dashboard Cite

INTRODUCTION: Perioperative myocardial infarction (PMI) after CABG can contribute to in-hospital morbidity and mortality, however, its clinical significance on long-term outcome, remains inadequately addressed. We studied both 30-day mortality and long-term effects of PMI in Icelandic CABG-patients. MATERIALS AND METHODS: A retrospective nationwide-study on 1446 consecutive CABG-patients operated at Landspitali in Iceland 2002-2018 without evidence of preoperative myocardial infarction. PMI was defined as a tenfold elevetion in serum-CK-MB associated with new ECG changes or diagnostic imaging consistent with ischemia. Patients with PMI were compared to a reference group with uni- and multivariate analyses. Long-term and MACCE-free survival were estimated with the Kaplan-Meier method and logistic regression used to determine factors associated with PMI. The mean follow-up time was 8.3 years. RESULTS: Out of 1446 patients 78 (5.4%) were diagnosed with PMI (range: 0-15.5%) with a significant annual decline in the incidence of PMI (12.7%, p<0.001). Over the same period preoperative aspirin use increased by 22.3% (p<0.018). PMI patients had a higher rate of short-term complications and a 11.5% 30-day mortality rate compared to 0.4% for non-PMI patients. PMI was found to be a predictor of 30-day mortality (OR 15.44, 95% CI: 6.89-34.67). PMI patients had worse 5-year MACCE-free survival (69.2% vs. 84.7, p=0,01), although overall survival was comparable between the groups. CONCLUSIONS: Although PMI after CABG is associated with significantly higher rates of short-term complications and 30-day mortality, long-term survival was similar to the reference group. Therefore, the mortality risk attributable to PMI appears to diminish after the immediate postoperative period.

show abstract

Section: Klínískar Breyturunclassified