Nothing but NET: A Case of Neuroendocrine Tumor in the Duodenal Bulb

An Unexpected Finding: Neuroendocrine Neoplasm in the Descending Duodenum

“…Her physical examination and Helicobacter pylori antigen detection showed no remarkable abnormalities. A computed tomography scan of the abdomen revealed a 0.5 x 0.5 cm well-defined hyperattenuating structure in the wall of the descending duodenum, which was confirmed by esophagogastroduodenoscopy demonstrating a 0.5 cm nodule in the descending duodenum (Fig gastrointestinal neuroendocrine tumors and 1% of all duodenal tumors, which are very rare (Baliss et al, 2021). The rarity of duodenal neuroendocrine tumors coupled with the absence of neuroendocrine clinical syndromes creates a noteworthy diagnostic challenge (Delle et al, 2016).…”

Same duodenal neuroendocrine tumors, different endoscopic resection methods: a case report and literature review

“…Neuroendocrine tumors (NETs), distinguished by their ability to secrete various biogenic amines and peptide hormones, are heterogeneous neoplasms derived from the secretory cells of the diffuse neuroendocrine system ( 1 ). Predominantly found in the gastroenteropancreatic tract and bronchopulmonary tree, duodenal NETs are particularly rare ( 1 ), accounting for only 2–3% of all gastrointestinal NETs and 1–3% of all duodenal tumors ( 2 ). However, possibly due to heightened awareness, the early detection of these tumors has increased, largely attributable to the widespread use of endoscopy and imaging techniques ( 3 ).…”