Argostemma glabra Joongku Lee, T.B. Tran & R.K. Choudhary, a new species of Rubiaceae from Khanh Hoa Province of Vietnam is described and illustrated. It is morphologically similar to A. apiculatum, but differs in its creeping habit, 4-6 flowered inflorescence, bigger and triangular bracts, smaller peduncle, bigger and broadly triangular calyx lobes, and non-apiculate and smaller corolla. Color photographs, a line drawing and a taxonomic key are provided to facilitate identification.