“…This sums to lead the conclusion that under the view of cytogenetic field, if patient with vaginal agenesis are excluded, the frequency of primary amenorrhea patients with abnormal chromosome constitutions are about 50%. To-date, 13 cases of primary amenorrhea in which autosomal aberrations were found have been referred to in the literature (Jascobs et al, 1961;Edwards, 1961 ;Hirschhorn, 1968;Ikeuchi et al, 1968;Kadotani et al, 1969;Sarto, 1974;Bhasin and Fuhrmann, 1976). In contrast, the present study had failed to demonstrate any one case showing autosomai aberrations.…”