“…For example, SDE via density gradient centrifugation or SDE via sublimation, are far much less known, but can be quite successfully used for practical enantiomeric purifications . Similarly to the distinct crystallographic structures observed in the solid state, chiral compounds in the liquid state or in solution show well‐defined preferences for homochiral/heterochiral dynamic molecular associations, accounting for various nonlinear effects, including SDE via chromatography ,,. Thus, when a solution of a nonracemic compound is subjected to chromatography, such dynamic homochiral/heterochiral molecular associations, having very different chromatographic behaviour, as compared with the corresponding monomers, result in the eluted material of gradually decreasing or increasing variable enantiomeric composition.…”