2016
DOI: 10.1016/j.ydbio.2016.08.012
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Notch and Hedgehog in the thymus/parathyroid common primordium: Crosstalk in organ formation

Abstract: Neves, Notch and Hedgehog in the thymus/parathyroid common primordium: Crosstalk in organ f o r m a t i o n , Developmental Biology, http://dx.doi.org/10. 1016/j.ydbio.2016.08.012 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting galley proof before it is published in its final citable form. Please note that … Show more

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Cited by 12 publications
(25 citation statements)
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“…Several of the Notch signaling receptors, ligands, modulators, and target genes are expressed in the pharyngeal arch region at stages of T/PT common primordium development [70,75,131,145]. In chicken embryos, Notch1 and the ligand Delta1 are faintly expressed in endoderm and neighboring cells of the 3PP.…”
Section: • Notch Signalingmentioning
confidence: 99%
See 3 more Smart Citations
“…Several of the Notch signaling receptors, ligands, modulators, and target genes are expressed in the pharyngeal arch region at stages of T/PT common primordium development [70,75,131,145]. In chicken embryos, Notch1 and the ligand Delta1 are faintly expressed in endoderm and neighboring cells of the 3PP.…”
Section: • Notch Signalingmentioning
confidence: 99%
“…The Notch targets, Hes1 and Hey1, are downstream of Tbx1 and Foxi3 in the development of the pharyngeal structures [70,145], and Hes1 is required for organs migration to their final destination [131]. Other Notch target genes, Hes5.1, Hes6.1, and Gata3, are expressed in the pharyngeal region of avian embryos [75]. In particular, Gata3 is expressed in T/PT common primordium and afterward is restricted to the Gcm2-domain when Foxn1-domain is established, both in chicken and mouse [73][74][75].…”
Section: • Notch Signalingmentioning
confidence: 99%
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“…The second, third and fourth pharyngeal arches are small (Moore-Scott and Manley, 2005). Like Nodal, Shh signaling is also required for normal development of the thyroid (Fagman et al, 2004;Moore-Scott and Manley, 2005;Bain et al, 2016;Figueiredo et al, 2016). Nodal and Hh cooperate in patterning the mesoderm, but whether they act together or in parallel in thyroid development has not been addressed.…”
Section: Nodal and Hh Function In Pharyngeal Patterning In Vertebratesmentioning
confidence: 99%