Nosocomial pertussis in neonatal units

Vaccination of healthcare workers: A review

“…158 Benefits and risks in healthcare settings Pertussis outbreaks in nosocomial settings are well-described in many countries with more than 30 reported nosocomial outbreaks. [160][161][162] The index cases were often found among healthcare staff, and B. pertussis transmission occurred more frequently among colleagues than between HCWs and their patients. [160][161][162] HCWs and patients may serve as pertussis sources in nosocomial outbreaks, which can result in substantial morbidity and constrain infection control measures.…”

“…[160][161][162] The index cases were often found among healthcare staff, and B. pertussis transmission occurred more frequently among colleagues than between HCWs and their patients. [160][161][162] HCWs and patients may serve as pertussis sources in nosocomial outbreaks, which can result in substantial morbidity and constrain infection control measures. [160][161][162] Pertussis HCW immunization, testing and limitation of patient contact in case of prolonged cough could reduce the morbidity of pertussis outbreaks.…”

“…[160][161][162] HCWs and patients may serve as pertussis sources in nosocomial outbreaks, which can result in substantial morbidity and constrain infection control measures. [160][161][162] Pertussis HCW immunization, testing and limitation of patient contact in case of prolonged cough could reduce the morbidity of pertussis outbreaks. [160][161][162] Currently, no RCT data support the effectiveness of pertussis vaccination in HCWs to prevent outbreaks and infant morbidity/mortality.…”

“…[160][161][162] Pertussis HCW immunization, testing and limitation of patient contact in case of prolonged cough could reduce the morbidity of pertussis outbreaks. [160][161][162] Currently, no RCT data support the effectiveness of pertussis vaccination in HCWs to prevent outbreaks and infant morbidity/mortality. [160][161][162][163] Furthermore, there are no approved protection correlates for pertussis vaccines.…”

“…[160][161][162] Currently, no RCT data support the effectiveness of pertussis vaccination in HCWs to prevent outbreaks and infant morbidity/mortality. [160][161][162][163] Furthermore, there are no approved protection correlates for pertussis vaccines. 164 However, recent modeling approaches are confirming that booster vaccination of pediatric HCWs is an effective intervention to reduce the risk of pertussis transmission 165 and is cost-effective or cost-saving, even at low coverage levels.…”