Nosocomial Outbreak of Pseudomonas aeruginosa Endophthalmitis

Abstract

We describe an outbreak of nosocomial endophthalmitis due to a common source, which was determined to be trypan blue solution prepared in the hospital's pharmacy service. We assume that viable bacteria probably gained access to the trypan blue stock solution during cooling after autoclaving. The temporal cluster ofPseudomonas aeruginosaendophthalmitis was readily perceived on the basis of clinical and microbiological findings, and an exogenous source of contamination was unequivocally identified by means of DNA fingerprinting.

Tetanus in a post operative patient—A case report

“…First is the use of inappropriate ventilation in the event of failed electricity supply. This allows bacterial contaminants including dust-laden tetanus spores to enter the operating room causing infection [13]. Second is sterilization of instruments on kerosene stoves, done when there is no power supply.…”

An outbreak of forty five cases of Pseudomonas aeruginosa acute endophthalmitis after phacoemulsification

“…Pseudomonas aeruginosa is one of the most common Gramne gative pathogens associated with nosocomial infections (14) . The epidemics seem to be related to contaminated intraocular irrigating solutions (6,7,9,12,14) . Pseudomonas was also identified in povidone-iodine solution (14) , at the fluid pathways of a phacoemulsifier (9) , water of autoclave (12) and air-conditioning system (14) .…”

“…The epidemics seem to be related to contaminated intraocular irrigating solutions (6,7,9,12,14) . Pseudomonas was also identified in povidone-iodine solution (14) , at the fluid pathways of a phacoemulsifier (9) , water of autoclave (12) and air-conditioning system (14) . Technics as high-resolution fluorescent amplified fragment length polymorphism ana lysis can identify the source of the outbreak to help preventing new ones (16) .…”

“…Outbreaks of postoperative P. aeruginosa endophthalmitis have been described in the literature (6)(7)(8)(9)(10)(11)(12)(13)(14) . The association with intrinsic contamination of ophthalmic solutions and contaminated instruments or equipment has been reported (6)(7)(8)(9)(10)(11)(12)(13) . The purpose of this study is describing an outbreak of Pseudomo nas aeruginosa endophthalmitis after cataract surgery, which occurred at one ophthalmological center of Eunapólis city, Bahia, Brazil.…”

Outbreak Investigations: Red-Eyed Rabbits and Community Service

“…The investigations of outbreaks of eye infection reported in this issue by AlonsoEchanove et al, 14 Hugonnet et al, 15 and Mateos et al 16 illustrate how a careful, methodical approach resulted in control of the outbreaks, advanced our knowledge of perioperative infection control in eye surgery, and addressed the potential utility of leukocyte-reduction filters for red blood cell transfusions. In the outbreaks studied by Hugonnet et al 15 and Mateos et al, 16 there were breaches of standard infection control procedures, including inadequate sterilization of equipment, extrinsic contamination of solutions, and failure to adhere to established surgical operative and postoperative standards. In the study by Alonso-Echanove et al, 14 use of filters that were designed to minimize systemic illness instead caused local eye reactions.…”