Nosocomial influenza in south-western Swiss hospitals during two seasonal epidemics: an observational study

Qalla-Widmer, L; Héquet, Delphine; Troillet, Nicolas; Petignat, Christiane; Balmelli, Carlo; Bassi, C.; Bellini, Chiara; Chave, Jean-Philippe; Cometta, A.; Christin, Laurent; Clerc, Olivier; Daher, O.; Fuehrer, Urs; Marchetti, Oscar; Merz, Liana R.; Portillo, Vera; Pralong, G.; Sandoz, L.; Senn, Laurence; Tâche, F.; Iten, Anne

doi:10.1016/j.jhin.2020.12.020

Cited by 4 publications

(3 citation statements)

References 34 publications

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“…In a well-designed prospective observational analysis, Qalla—Widmer and co-workers confirmed the general findings of Godoy et al [ 14 , 15 ]. Across over 5000 subjects hospitalized for influenza, these researchers identified 836 instances where influenza infection began more than 72 h after hospital admission [ 15 ]. This resulted in an incidence of 0.5 influenza NP cases per 1000 hospitalizations.…”

Section: Studies Of Specific Virusessupporting

confidence: 70%

Respiratory Viruses in Nosocomial Pneumonia: An Evolving Paradigm

Zilberbeg¹,

Khan

Shorr

2023

Viruses

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Nosocomial pneumonia (NP) represents a leading cause of morbidity and mortality in hospitalized patients. Historically, clinicians have considered hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), which comprise NP, to be essentially bacterial processes. As such, patients suspected of having either HAP or VAP are initially treated with broad-spectrum antibiotics, and few clinicians search for a possible culprit virus. Recent reports which build on earlier studies, however, indicate that viruses likely play an important role in NP. Studies employing viral diagnostics as part of the evaluation for NP indicate that common respiratory viruses can spread nosocomially and lead to HAP and VAP. Similarly, studies of the general epidemiology of respiratory viral infections, such as influenza, respiratory syncytial virus, adenovirus, and rhinovirus, confirm that these pathogens are important causes of NP, especially among immunosuppressed and pediatric patients. More importantly, these more contemporary analyses reveal that one cannot, based on clinical characteristics, distinguish a viral from a bacterial cause of NP. Additionally, viral HAP and VAP result in crude mortality rates that rival or exceed those reported in bacterial NP. Rigorous prospective, multicenter trials are needed to confirm the significance of respiratory viruses in NP, as are studies of novel therapeutics for these viral infections.

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Section: Studies Of Specific Virusessupporting

confidence: 70%

Respiratory Viruses in Nosocomial Pneumonia: An Evolving Paradigm

Zilberbeg¹,

Khan

Shorr

2023

Viruses

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“…In the UK alone, excess influenza deaths are modelled to exceed 20,000 during some seasons [2] , around 95% of which occur in those aged over 65 [3] . In one Swiss region, 0.5% of all admissions received a diagnosis of nosocomial influenza [4] .…”

Section: Introductionmentioning

confidence: 99%

Nosocomial acquisition of influenza is associated with significant morbidity and mortality: Results of a prospective observational study

Snell¹,

Vink²,

Verlander³

et al. 2022

Journal of Infection and Public Health

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“…Recent studies indicate that healthcare-associated influenza is a major component of the burden of influenza in healthcare facilities, accounting for up to 17.3% of influenza cases with considerable range from season to season [ 5 , 6 ]. Healthcare-associated influenza is associated with complications and significant mortality mainly among vulnerable patients with comorbidities [ 7 , 8 , 9 ]. Moreover, healthcare personnel (HCP) have long been recognized as an occupational group highly affected by influenza, but also for transmission of influenza virus to their patients and colleagues and onset of outbreaks with significant morbidity, mortality, and disruption of healthcare services [ 3 , 4 , 10 , 11 , 12 , 13 , 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Influenza Vaccination Programs for Healthcare Personnel: Organizational Issues and Beyond

Maltezou

Ioannidou

Schrijver

et al. 2021

IJERPH

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Healthcare personnel (HCP) are a high priority group for influenza vaccination aiming to protect them but also to protect vulnerable patients and healthcare services from healthcare-associated influenza and HCP absenteeism. Multi-component influenza vaccination programs targeting behavioral, organizational, and administrative barriers are critical, if influenza vaccination rates among HCP are to be raised on a sustained basis. Mandatory influenza vaccination policy is the only single intervention that can achieve high and sustainable vaccination rates in HCP in short term. In this article, we provide an overview of issues pertaining to influenza vaccination of HCP, with an emphasis on organizational issues of influenza vaccination programs.

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Nosocomial influenza in south-western Swiss hospitals during two seasonal epidemics: an observational study

Cited by 4 publications

References 34 publications

Respiratory Viruses in Nosocomial Pneumonia: An Evolving Paradigm

Respiratory Viruses in Nosocomial Pneumonia: An Evolving Paradigm

Nosocomial acquisition of influenza is associated with significant morbidity and mortality: Results of a prospective observational study

Influenza Vaccination Programs for Healthcare Personnel: Organizational Issues and Beyond

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